CAS No. 96-88-8

Batch: Purity:98
Mepivacaine Chemical Structure
Chemical Structure
Check the Mepivacaine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 96-88-8
Molecular Formula

C15H22N2O

Molecular Weight (MW) 246.35
SMILES CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C

Ordering Information

Biological Activity

Mepivacaine is a voltage-gated sodium channel inhibitor that functions as a local anesthetic agent. By binding to voltage-gated sodium channels on the neuronal membrane, it prevents the influx of sodium ions necessary for signal depolarization. This inhibition suppresses action potential propagation along peripheral nerves, ultimately blocking the transmission of pain signals and mediating localized sensory anesthesia.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 49 mg/mL (198.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.