CAS No. 10563-70-9

Batch: Purity:99.81
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Melitracen hydrochloride Chemical Structure
Chemical Structure
Check the Melitracen hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 10563-70-9
Molecular Formula

C21H25N.HCl
Molecular Weight (MW) 327.89
SMILES CC1(C2=CC=CC=C2C(=CCCN(C)C)C3=CC=CC=C31)C.Cl

Biological Activity

Melitracen hydrochloride is a tricyclic compound that acts as a dopamine D1 and D2 receptor antagonist with antidepressant properties. By modulating dopaminergic and monoaminergic signaling pathways, it alters neurotransmitter receptor dynamics and downstream cellular responses. These biochemical interactions contribute to its observed effects on neural activity and central nervous system function.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 65 mg/mL (198.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 65 mg/mL
Ethanol 65 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.