CAS No. 10095-06-4
Batch:
Purity:99.92
Chemical Structure
Check the
Mebicar
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1,3,4,6-tetramethyl-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione | |
|---|---|---|
| CAS Number | 10095-06-4 | |
| Molecular Formula |
C8H14N4O2 |
|
| Molecular Weight (MW) | 198.22 | |
| SMILES | CN1C2C(N(C)C1=O)N(C)C(=O)N2C | |
| InChIKey | XIUUSFJTJXFNGH-UHFFFAOYSA-N |
Mebicar is a bicyclic bis-urea derivative that acts as an anxiolytic agent by modulating neurotransmitter systems in the central nervous system. It displays central adrenolytic activity, alters norepinephrine metabolism in the brain stem, and inhibits orientation reactions in animals. Through these neuromodulatory effects, mebicar decreases noradrenaline levels while increasing brain serotonin levels, thereby reducing fear and anxiety responses without inducing muscle relaxation. [1][2]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
40 mg/mL
(201.79 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 40 mg/mL |
| Ethanol | 40 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.