Cell-free Assays (IC50/Ki) for Marimastat (BB-2516)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| D. typus crude venom | 34.2 nM | Absorbance-based plasma clotting assay, fitted with a nonlinear regression curve for the normalised response (variable slope) | Download PDF |
| D. russelii venom (Karnataka: KA) | 1.977 μM | Azocasein assay, absorbance measured at 440 nm, non-linear regression curve fitting. | PMC12152178 |
| D. russelii venom (Madhya Pradesh: MP) | 1.508 μM | Azocasein assay, absorbance measured at 440 nm, non-linear regression curve fitting. | PMC12152178 |
| D. russelii venom (Rajasthan: RJ) | 1.667 μM | Azocasein assay, absorbance measured at 440 nm, non-linear regression curve fitting. | PMC12152178 |
| D. russelii venom (Andhra Pradesh: AP) | 1.957 μM | Azocasein assay, absorbance measured at 440 nm, non-linear regression curve fitting. | PMC12152178 |
| D. russelii venom (Goa: GA) | 2.33 μM | Azocasein assay, absorbance measured at 440 nm, non-linear regression curve fitting. | PMC12152178 |
| MMP-9 | 3 nM | Literature data (MMP inhibition assay) | Download PDF |
| MMP-1 | 5 nM | Literature data (MMP inhibition assay) | Download PDF |
| MMP-2 | 6 nM | Literature data (MMP inhibition assay) | Download PDF |
| MMP-14 | 9 nM | Literature data (MMP inhibition assay) | Download PDF |
| MMP-7 | 13 nM | Literature data (MMP inhibition assay) | Download PDF |
Cell-based Assay (IC50) for Marimastat (BB-2516)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Check the
Marimastat (BB-2516)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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- Marimastat (BB-2516) Mechanism of Action: SVMP Inhibition in Endothelial Cell Research
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