CAS No. 140678-14-4
Chemical Structure
Check the
Mangafodipir Trisodium
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 140678-14-4 | |
|---|---|---|
| Molecular Formula |
C22H24MnN4O14P2.3H.3Na |
|
| Molecular Weight (MW) | 757.32 | |
| SMILES | [Na+].[Na+].[Na+].[Mn++]|1|2|3|4|5|[O-]C(=O)CN|1(CCN|2(CC([O-]|3)=O)CC6=C(CO[P]([O-])([O-])=O)C=NC(=C6[O-]|4)C)CC7=C(CO[P]([O-])([O-])=O)C=NC(=C7[O-]|5)C.[H+].[H+].[H+] |
Biological Activity
Mangafodipir trisodium is a hepatocellular-specific MRI contrast agent and superoxide dismutase mimetic that attenuates cellular oxidative stress. By mimicking endogenous superoxide dismutase activity and scavenging reactive oxygen species, it alleviates chemotherapy-induced peripheral neuropathy and protects normal tissues against chemotherapy-mediated damage. Importantly, mangafodipir trisodium exerts these cytoprotective effects without compromising the tumoricidal activity of co-administered chemotherapeutic regimens. [1]
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Reference
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Note: Technical data last updated: Sep 1, 2026.