CAS No. 7786-30-3

Batch: Purity:98
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Magnesium chloride Chemical Structure
Chemical Structure
Check the Magnesium chloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 7786-30-3
Molecular Formula

Cl2Mg
Molecular Weight (MW) 95.21
SMILES [Mg++].[Cl-].[Cl-]

Biological Activity

Magnesium chloride is an inorganic ionic salt that acts as an essential cofactor for blood coagulation factors and metabolic enzymes. Exogenous magnesium chloride reduces activated partial thromboplastin times (aPTT) in lupus anticoagulant-positive samples and accelerates tissue factor-induced coagulation. Divalent magnesium ions interact with specific coagulation proteins to enhance factor X activation, thereby modulating intrinsic and extrinsic hemostatic pathways to influence blood clotting kinetics. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 19 mg/mL
Ethanol 19 mg/mL
DMSO 10 mg/mL (105.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Tokutake T, et al. PLoS One. 2016;11(6):e0157835.

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Note: Technical data last updated: Sep 1, 2026.