CAS No. 19908-48-6
Batch:
Purity:98.24
Chemical Structure
Check the
Maackiain
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 19908-48-6 | |
|---|---|---|
| Molecular Formula |
C16H12O5 |
|
| Molecular Weight (MW) | 284.26 | |
| SMILES | C1C2C(C3=C(O1)C=C(C=C3)O)OC4=CC5=C(C=C24)OCO5 |
Maackiain is a naturally occurring pterocarpan derivative that functions as a bioactive plant secondary metabolite with anticancer and antimicrobial activities. It suppresses cancer cell proliferation and modulates inflammatory pathway signals, contributing to reduced cellular growth and pathogenic inhibition. Furthermore, maackiain acts as a selective inhibitor of human monoamine oxidase-B, altering neurotransmitter metabolism and downstream cellular phenotypes in preclinical models.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
56 mg/mL
(197.0 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
56 mg/mL
(197.0 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.