SMILES:

N[S](=O)(=O)C1=CC=C(NC(=O)C2=C(O)C3=C(NC2=O)SC4=C3CCCC4)C=C1
M435-1279 Chemical Structure
Chemical Structure
Check the M435-1279 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-hydroxy-2-oxo-N-(4-sulfamoylphenyl)-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-b]pyridine-3-carboxamide
CAS Number 1359431-16-5
Molecular Formula

C18H17N3O5S2
Molecular Weight (MW) 419.48
SMILES N[S](=O)(=O)C1=CC=C(NC(=O)C2=C(O)C3=C(NC2=O)SC4=C3CCCC4)C=C1
InChIKey MVQJFYRZMPKNIV-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 9 mg/mL (21.45 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.