CAS No. 52-76-6

Batch: Purity:98
Lynestrenol Chemical Structure
Chemical Structure
Check the Lynestrenol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 52-76-6
Molecular Formula

C20H28O

Molecular Weight (MW) 284.44
SMILES CC12CCC3C(C1CCC2(C#C)O)CCC4=CCCCC34

Biological Activity

Lynestrenol is a synthetic progestational hormone that functions as an agonist of the progesterone receptor while exhibiting weak androgenic and estrogenic activities. Upon interacting with steroid hormone receptors, it modulates downstream gene transcription and regulates hormone-responsive pathways. These downstream functional actions lead to the alteration of cellular proliferation and differentiation phenotypes in target tissues. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 56 mg/mL (196.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

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Note: Technical data last updated: Sep 1, 2026.