LY411575 is a potent γ-secretase and Notch inhibitor. It affects the Notch signaling pathway, and by blocking γ-secretase-mediated cleavage, it inhibits tumor proliferation and fibrosis, while promoting sensory neuronal generation and BCMA-targeted immune killing.
LY411575 Mechanism of Action: Gamma-secretase Inhibition in Tumor Cell Research
LY411575 MOA：Targeting Gamma-secretase/Notch Signaling Pathway for Oncology