CAS No. 367514-88-3
Batch:
Purity:99.97
Chemical Structure
Check the
Lurasidone HCl
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 367514-88-3 | |
|---|---|---|
| Molecular Formula |
C28H36N4O2S.HCl |
|
| Molecular Weight (MW) | 529.14 | |
| SMILES | C1CCC(C(C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)C6C7CCC(C7)C6C5=O.Cl |
Lurasidone HCl is an atypical antipsychotic that inhibits dopamine D2 (IC50 1.68 nM), 5-HT2A (IC50 2.03 nM), 5-HT7 (IC50 0.495 nM), 5-HT1A (IC50 6.75 nM), and noradrenaline alpha2C (IC50 10.8 nM). By modulating G-protein coupled receptor pathways, it regulates dopaminergic and serotonergic neurotransmission, demonstrating potent antipsychotic-like and antidepressant-like phenotypic effects in animal behavioral models.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| 4-Methylpyridine | 15 mg/mL |
| DMSO |
1 mg/mL
(1.88 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.