CAS No. 545-47-1

Batch: Purity:100.00
Check CoA
Lupeol Chemical Structure
Chemical Structure
Check the Lupeol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 545-47-1
Molecular Formula

C30H50O
Molecular Weight (MW) 426.72
SMILES CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C

Ordering Information

Biological Activity

Lupeol is a dietary lupane-type triterpene possessing multi-target anti-inflammatory and antineoplastic activities. It modulates key cellular signaling cascades, including the NF-κB and PI3K/AKT pathways, leading to the inhibition of inflammatory mediators such as TNF-α and IL-1β. These molecular perturbations suppress cell proliferation, induce G1-phase cell cycle arrest, and trigger apoptotic cell death across multiple cancer cell types. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 3 mg/mL (7.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.