CAS No. 621-59-0
Batch:
Purity:99.99
Chemical Structure
Check the
Isovanillin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 621-59-0 | |
|---|---|---|
| Molecular Formula |
C8H8O3 |
|
| Molecular Weight (MW) | 152.15 | |
| SMILES | COC1=C(C=C(C=C1)C=O)O |
Biological Activity
Isovanillin is a synthetic small-molecule, reversible inhibitor of aldehyde oxidase (AO). By directly inhibiting aldehyde oxidase activity, it modulates the oxidative metabolism of various aromatic aldehydes and xenobiotic compounds. This enzymatic inhibition suppresses aldehyde oxidase-mediated biotransformation pathways, thereby modulating downstream drug metabolism cascades and altering the bioactivation and clearance rates of therapeutic agents metabolized by this hepatic enzyme.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(197.17 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.