CAS No. 119425-89-7
Batch:
Purity:99.99
Chemical Structure
Check the
Loureirin A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one | |
|---|---|---|
| CAS Number | 119425-89-7 | |
| Molecular Formula |
C17H18O4 |
|
| Molecular Weight (MW) | 286.32 | |
| SMILES | COC1=CC=C(CCC(=O)C2=CC=C(O)C=C2)C(=C1)OC | |
| InChIKey | RSAIVLRELNGZEY-UHFFFAOYSA-N |
Loureirin A is a natural flavonoid extracted from the red resin of Dracaena cochinchinensis that targets the PI3K/Akt signaling pathway. Inhibition of Akt phosphorylation impairs downstream PI3K/Akt pathway activation and cellular signal transduction. This targeted attenuation leads to suppressed platelet activation, demonstrating the critical role of PI3K/Akt signaling in mediating functional platelet responses and thrombotic activity. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(349.25 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.