CAS No. 53882-12-5
Chemical Structure
Check the
Lodoxamide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 53882-12-5 | |
|---|---|---|
| Molecular Formula |
C11H6ClN3O6 |
|
| Molecular Weight (MW) | 311.64 |
Lodoxamide is a potent agonist of G protein-coupled receptor 35 (GPR35) that functions as a mast cell stabilizer. Activation of GPR35 by lodoxamide suppresses mast cell degranulation and inhibits the release of proinflammatory mediators, including eosinophil peroxidase, eosinophil cationic protein, and eosinophil-derived neurotoxin after IgA stimulation. These cellular actions mitigate eosinophil activation and attenuate localized allergic inflammatory responses.
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Note: Technical data last updated: Sep 1, 2026.