Lobeline hydrochloride

Catalog No.S3972

Lobeline hydrochloride Chemical Structure

Molecular Weight(MW): 373.92

Lobeline hydrochloride is an alkaloid that acts on nicotinic cholinergic receptors but is less potent than nicotine. It is also a VMAT2 ligand and an antagonist of μ-opioid receptors.

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Biological Activity

Description Lobeline hydrochloride is an alkaloid that acts on nicotinic cholinergic receptors but is less potent than nicotine. It is also a VMAT2 ligand and an antagonist of μ-opioid receptors.

Protocol

References

Solubility (25°C)

In vitro DMSO 74 mg/mL (197.9 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 373.92
Formula

C22H27NO2.HCl

CAS No. 134-63-4
Storage powder
in solvent
Synonyms N/A

Bio Calculators

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00664703 Completed Attention Deficit Disorder With Hyperactivity Yaupon Therapeutics|National Institute of Mental Health (NIMH) July 2008 Phase 2
NCT00519259 Unknown status Methamphetamine Dependence National Institute on Drug Abuse (NIDA) February 2006 Phase 1
NCT00100074 Unknown status Amphetamine-Related Disorders National Institute on Drug Abuse (NIDA) September 2004 Phase 1
NCT00439504 Unknown status Methamphetamine Dependence National Institute on Drug Abuse (NIDA) null Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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AChR Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID