CAS No. 28831-65-4

Batch: Purity:99.66
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Lithospermic acid Chemical Structure
Chemical Structure
Check the Lithospermic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 28831-65-4
Molecular Formula

C27H22O12
Molecular Weight (MW) 538.46
SMILES C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C(C(OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)O)O)O

Ordering Information

Biological Activity

Lithospermic acid is a natural polyphenolic compound isolated from Salvia miltiorrhiza radix with antihypertensive and antioxidant activities. It reduces reactive oxygen species accumulation and attenuates oxidative stress-induced cellular damage. By modulating cellular antioxidant pathways and scavenging free radicals, lithospermic acid supports vascular endothelial homeostasis and protects against oxidative injury in cardiovascular and neuronal tissues.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (185.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
Ethanol 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.