CAS No. 2245072-21-1

Batch: Purity:99.22
LIT-001 trifluoroacetate Chemical Structure
Chemical Structure
Check the LIT-001 trifluoroacetate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 2245072-21-1
Molecular Formula

C30H34F3N7O4S

Molecular Weight (MW) 645.7

Ordering Information

Biological Activity

LIT-001 trifluoroacetate is a potent, nonpeptide oxytocin receptor (OXTR) agonist. By selectively activating OXTR, the compound engages downstream G protein-coupled receptor signaling cascades to modulate neuroendocrine functions in the central nervous system. This pathway regulation enhances social attachment behaviors, reverses social interaction deficits in animal models of autism spectrum disorder, and produces durable antinociceptive effects against inflammatory pain. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (154.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 100 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.