CAS No. 7179-49-9
Batch:
Purity:98
Chemical Structure
Check the
Lincomycin Hydrochloride Monohydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S,4R)-N-[(1R,2R)-2-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrate;hydrochloride | |
|---|---|---|
| CAS Number | 7179-49-9 | |
| Molecular Formula |
C18H34N2O6S.HCl.H2O |
|
| Molecular Weight (MW) | 461.01 | |
| SMILES | CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)O.O.Cl | |
| InChIKey | LFZGYTBWUHCAKF-DCNJEFSFSA-N |
Lincomycin Hydrochloride Monohydrate is a narrow-spectrum lincosamide antibiotic that targets the 50S ribosomal subunit in susceptible bacteria. By binding to 23S ribosomal RNA at the peptidyl transferase domain, it inhibits bacterial protein synthesis by interfering with peptide bond formation during elongation. This suppression of protein synthesis leads to antibacterial activity against Gram-positive organisms, including staphylococcal and streptococcal species, as well as anaerobic pathogens like Bacteroides fragilis. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
92 mg/mL
(199.56 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Lincomycin Hydrochloride Monohydrate Solubility in DMSO
- Lincomycin Hydrochloride Monohydrate Stock Solution
- Lincomycin Hydrochloride Monohydrate Storage
- Lincomycin Hydrochloride Monohydrate Stability
- Lincomycin Hydrochloride Monohydrate Molecular Weight
- Lincomycin Hydrochloride Monohydrate SMILES
- Lincomycin Hydrochloride Monohydrate Chemical Structure (2D and 3D)
- Lincomycin Hydrochloride Monohydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.