CAS No. 260413-62-5

Batch: Purity:99.69
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ligustroflavone Chemical Structure
Chemical Structure
Check the ligustroflavone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 260413-62-5
Molecular Formula

C33H40O18
Molecular Weight (MW) 724.66
SMILES CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)OC6C(C(C(C(O6)C)O)O)O)O)O)O)O)O

Ordering Information

Biological Activity

Ligustroflavone is a natural flavonoid compound that acts as an AMPK activator with potent antioxidant properties. By stimulating AMP-activated protein kinase (AMPK) signaling, it regulates cellular energy homeostasis and modulates downstream metabolic pathways. Activation of this axis attenuates oxidative stress, reduces intracellular reactive oxygen species accumulation, and promotes cytoprotective cellular responses. Consequently, ligustroflavone serves as a valuable tool for investigating energy metabolism and stress responses. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (137.99 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.