CAS No. 23672-07-3

Batch: Purity:99.96
Levosulpiride Chemical Structure
Chemical Structure
Check the Levosulpiride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 23672-07-3
Molecular Formula

C15H23N3O4S

Molecular Weight (MW) 341.43
SMILES CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

Biological Activity

Levosulpiride is a selective antagonist of dopamine D2 receptors that acts as both an antipsychotic and a prokinetic agent. By selectively inhibiting D2 autoreceptors and postsynaptic receptors, it enhances acetylcholine release in the gastrointestinal tract and modulates central dopaminergic pathways. This targeted antagonism promotes gastric emptying, improves gastrointestinal motility, and modulates behavioral phenotypes associated with dopaminergic dysfunction.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 69 mg/mL (202.09 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.