CAS No. 175131-60-9

Batch: Purity:99.99
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Levomilnacipran Hydrochloride Chemical Structure
Chemical Structure
Check the Levomilnacipran Hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name cis-(1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide;hydrochloride
CAS Number 175131-60-9
Molecular Formula

C15H23ClN2O
Molecular Weight (MW) 282.81
SMILES CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2.Cl
InChIKey XNCDYJFPRPDERF-NQQJLSKUSA-N

Ordering Information

Biological Activity

Levomilnacipran Hydrochloride is a potent, selective serotonin and norepinephrine reuptake inhibitor (SNRI). By targeting the serotonin transporter (SERT) and norepinephrine transporter (NET), it inhibits monoamine neurotransmitter reuptake, leading to elevated synaptic levels of serotonin and norepinephrine within central nervous system pathways. These downstream neurochemical adjustments enhance monoaminergic neurotransmission and produce robust antidepressant phenotypes in preclinical models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 57 mg/mL (201.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 57 mg/mL
Ethanol 57 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.