CAS No. 24735-18-0
Batch:
Purity:99.74
Chemical Structure
Check the
Leonurine Hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 24735-18-0 | |
|---|---|---|
| Molecular Formula |
C14H22ClN3O5 |
|
| Molecular Weight (MW) | 347.79 | |
| SMILES | COC1=CC(=CC(=C1O)OC)C(=O)OCCCCN=C(N)N.Cl |
Leonurine Hydrochloride (SCM-198) is a natural alkaloid anti-glycation agent with vasodilator, antioxidant, cardioprotective, and neuroprotective activities. It modulates oxidative stress and inflammatory signaling pathways, including NF-kB and AKT pathways, to suppress reactive oxygen species production and inhibit pro-inflammatory cytokine expression. These downstream functions contribute to attenuated cellular apoptosis and enhanced cell survival in cardiovascular and neuronal models.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
70 mg/mL
(201.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 7 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Leonurine Hydrochloride Solubility in DMSO
- Leonurine Hydrochloride Stock Solution
- Leonurine Hydrochloride Storage
- Leonurine Hydrochloride Stability
- Leonurine Hydrochloride Molecular Weight
- Leonurine Hydrochloride SMILES
- Leonurine Hydrochloride Chemical Structure (2D and 3D)
- Leonurine Hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.