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E7080 (Lenvatinib) is a potent, multi-targeted VEGFR, FGFR, PDGFR, and RET kinase inhibitor. It affects PI3K/AKT/mTOR and RAF/MEK/ERK signaling pathways, and by blocking these receptor tyrosine kinases, it inhibits tumor cell proliferation, migration, and angiogenesis, while promoting apoptosis.