CAS No. 25999-31-9
Batch:
Purity:99.62
Chemical Structure
Check the
Lasalocid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 25999-31-9 | |
|---|---|---|
| Molecular Formula |
C34H54O8 |
|
| Molecular Weight (MW) | 590.79 |
Biological Activity
Lasalocid is a carboxylic polyether ionophore antibiotic that acts by binding and transporting monovalent and divalent cations across lipid membranes, disrupting cellular ion gradients. By altering transmembrane sodium, potassium, and calcium balance, it causes osmotic swelling, intracellular ion imbalance, and cell lysis in targeted protozoan parasites such as Eimeria species. These actions disrupt transmembrane potential and impair cellular energy metabolism, inhibiting coccidial development.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(169.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 6 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.