CAS No. 571170-77-9
Batch:
Purity:99.96
Chemical Structure
Check the
Laropiprant
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 571170-77-9 | |
|---|---|---|
| Molecular Formula |
C21H19CIFNO4S |
|
| Molecular Weight (MW) | 435.90 |
Laropiprant is a potent and selective prostaglandin D2 (DP) receptor antagonist. By selectively blocking the DP receptor, laropiprant inhibits intracellular cyclic AMP signaling pathways driven by PGDThis targeted receptor antagonism suppresses downstream cellular phenotypes, including PGD2-induced cutaneous vasodilation and allergic inflammatory responses, while displaying high selectivity over other prostanoid receptor family members. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
87 mg/mL
(199.58 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 87 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.