Molecular Weight: 501.8 g/mol
Chemical Structure
Check the
Laduviglusib (CHIR-99021) Hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(199.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | 1.5 mg/mL |
| DMSO |
100 mg/mL
(199.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 10 mg/mL |
| Water | Insoluble |
| DMSO |
33 mg/mL
(65.76 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 33 mg/mL |
| Ethanol | 5 mg/mL |
| DMSO |
100 mg/mL
(199.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(199.28 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 6 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | 6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile;hydrochloride | |
|---|---|---|
| CAS Number | 1797989-42-4 | |
| Molecular Formula |
C22H18Cl2N8.HCl |
|
| Molecular Weight (MW) | 501.8 | |
| SMILES | CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N.Cl | |
| InChIKey | SCQDMKUZHIGAIB-UHFFFAOYSA-N |
- Laduviglusib (CHIR-99021) Hydrochloride Mechanism of Action: GSK-3β Inhibition in Pluripotent Stem Cell Research
- Laduviglusib (CHIR-99021) Hydrochloride: Selectivity & Specificity
- Laduviglusib (CHIR-99021) Hydrochloride Working Concentration | Cell Culture | Treatment
- Laduviglusib (CHIR-99021) Hydrochloride Solubility in DMSO
- Laduviglusib (CHIR-99021) Hydrochloride Stock Solution
- Laduviglusib (CHIR-99021) Hydrochloride Storage
- Laduviglusib (CHIR-99021) Hydrochloride Stability
- Laduviglusib (CHIR-99021) Hydrochloride VS GSK-3 Inhibitor IX (BIO)
- Laduviglusib (CHIR-99021) Hydrochloride SMILES
- Laduviglusib (CHIR-99021) Hydrochloride CAS Number
- Laduviglusib (CHIR-99021) Hydrochloride Chemical Structure (2D and 3D)
- Laduviglusib (CHIR-99021) Hydrochloride IC50 for Cell-based and Cell-free Assays
- Laduviglusib (CHIR-99021) Hydrochloride Sigma (AMBH2D6F7D7A)? Try a better option.
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- Laduviglusib (CHIR-99021) Hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.