CAS No. 147-85-3
Batch:
Purity:99.99
Chemical Structure
Check the
L-Proline
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-pyrrolidine-2-carboxylic acid | |
|---|---|---|
| CAS Number | 147-85-3 | |
| Molecular Formula |
C5H9NO2 |
|
| Molecular Weight (MW) | 115.13 | |
| SMILES | C1CC(NC1)C(=O)O | |
| InChIKey | ONIBWKKTOPOVIA-BYPYZUCNSA-N |
L-Proline is a non-essential proteinogenic amino acid that serves as a fundamental building block for collagen biosynthesis and protein structure. It plays a critical role in maintaining cellular redox balance, extracellular matrix stability, and connective tissue integrity. Through its conversion to hydroxyproline and involvement in metabolic pathways, L-Proline supports tissue repair, cell survival, and joint function under physiological and stress conditions. [1][2]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 23 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.