CAS No. 3105-95-1

Batch: Purity:99.64
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L(-)-Pipecolinic acid Chemical Structure
Chemical Structure
Check the L(-)-Pipecolinic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 3105-95-1
Molecular Formula

C6H11NO2
Molecular Weight (MW) 129.16
SMILES C1CCNC(C1)C(=O)O

Ordering Information

Biological Activity

L(-)-Pipecolinic acid is an endogenous amino acid metabolite and a central intermediate in the L-lysine catabolic pathway in mammals. As a naturally occurring derivative of proline, L(-)-pipecolinic acid present in human blood modulates central nervous system activity through interaction with GABAergic signaling pathways. Elevated levels of L(-)-pipecolinic acid are associated with peroxisomal metabolic disorders, highlighting its critical involvement in human amino acid homeostasis and neuronal synaptic regulation.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 26 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.