CAS No. 63-91-2

Batch: Purity:99.94
L-Phenylalanine Chemical Structure
Chemical Structure
Check the L-Phenylalanine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 63-91-2
Molecular Formula

C9H11NO2

Molecular Weight (MW) 165.19

Ordering Information

Biological Activity

L-Phenylalanine is an essential amino acid that functions as a competitive antagonist at N-methyl-D-aspartate receptor (NMDAR) glycine- and glutamate-binding sites. By blocking NMDAR activation, it modulates downstream glutamatergic signaling pathways and influences synaptic transmission in the central nervous system. Additionally, as a precursor in catecholamine biosynthesis, L-phenylalanine regulates downstream neurotransmitter production, impacting neuronal function and cellular metabolic phenotypes. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 16 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.