CAS No. 1483-01-8
Batch:
Purity:98
Chemical Structure
Check the
L-Homoarginine hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-2-amino-6-(diaminomethylideneamino)hexanoic acid;hydrochloride | |
|---|---|---|
| CAS Number | 1483-01-8 | |
| Molecular Formula |
C7H16N4O2.HCl |
|
| Molecular Weight (MW) | 224.69 | |
| SMILES | C(CCN=C(N)N)CC(C(=O)O)N.Cl | |
| InChIKey | YMKBVNVCKUYUDM-JEDNCBNOSA-N |
L-Homoarginine hydrochloride is an amino acid derivative that acts as a selective, uncompetitive inhibitor of liver-type alkaline phosphatase, also designated as tissue-nonspecific alkaline phosphatase (TNAP). By inhibiting TNAP activity, it reduces extracellular inorganic pyrophosphate hydrolysis and modulates local phosphate homeostasis, downstream influencing matrix mineralization, osteogenic differentiation, and vascular calcification signaling pathways in preclinical models. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 44 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- L-Homoarginine hydrochloride Solubility in DMSO
- L-Homoarginine hydrochloride Stock Solution
- L-Homoarginine hydrochloride Storage
- L-Homoarginine hydrochloride Stability
- L-Homoarginine hydrochloride Molecular Weight
- L-Homoarginine hydrochloride SMILES
- L-Homoarginine hydrochloride Chemical Structure (2D and 3D)
- L-Homoarginine hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.