CAS No. 71-00-1

Batch: Purity:99.85
L-​Histidine Chemical Structure
Chemical Structure
Check the L-​Histidine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 71-00-1
Molecular Formula

C6H9N3O2

Molecular Weight (MW) 155.15
SMILES C1=C(NC=N1)CC(C(=O)O)N

Ordering Information

Biological Activity

L-Histidine is an essential α-amino acid required for protein biosynthesis and cellular growth. As a fundamental building block of proteins, it plays crucial roles in enzymatic catalysis, buffering intracellular pH, and maintaining tissue repair processes. L-Histidine also serves as a precursor for histamine synthesis and scavenging reactive oxygen species to modulate downstream inflammatory and metabolic pathways. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 31 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.