CAS No. 5934-29-2
Batch:
Purity:99.58
Chemical Structure
Check the
L-Histidine monohydrochloride monohydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;hydrate;hydrochloride | |
|---|---|---|
| CAS Number | 5934-29-2 | |
| Molecular Formula |
C6H12ClN3O3 |
|
| Molecular Weight (MW) | 209.63 | |
| SMILES | O.Cl.NC(CC1=CN=C[NH]1)C(O)=O | |
| InChIKey | CMXXUDSWGMGYLZ-XRIGFGBMSA-N |
L-Histidine monohydrochloride monohydrate is an essential amino acid derivative and metabolic component involved in protein biosynthesis pathways. By serving as an amino acid supply and participating in cellular amino acid sensing, it influences protein synthesis and stress response signaling networks. Modulation of amino acid availability directly affects translation initiation and cellular metabolic homeostasis, producing differential growth and survival responses in normal versus tumorigenic cell lines. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 42 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- L-Histidine monohydrochloride monohydrate Solubility in DMSO
- L-Histidine monohydrochloride monohydrate Stock Solution
- L-Histidine monohydrochloride monohydrate Storage
- L-Histidine monohydrochloride monohydrate Stability
- L-Histidine monohydrochloride monohydrate Molecular Weight
- L-Histidine monohydrochloride monohydrate SMILES
- L-Histidine monohydrochloride monohydrate Chemical Structure (2D and 3D)
- L-Histidine monohydrochloride monohydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.