CAS No. 41372-08-1
Batch:
Purity:99.69
Chemical Structure
Check the
L-(-)-α-Methyldopa hydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 41372-08-1 | |
|---|---|---|
| Molecular Formula |
C20H32N2O11 |
|
| Molecular Weight (MW) | 476.47 | |
| SMILES | O.O.O.CC(N)(CC1=CC(=C(O)C=C1)O)C(O)=O.CC(N)(CC2=CC(=C(O)C=C2)O)C(O)=O |
L-(-)-α-Methyldopa hydrate is a potent antihypertensive drug that functions as a selective agonist for α2-adrenergic receptors. Following central conversion into α-methylnorepinephrine, it selectively activates presynaptic α2-adrenergic receptors within the brainstem, thereby suppressing central sympathetic nervous system outflow to heart and blood vessels. This pathway inhibition attenuates vascular tone, decreases total peripheral resistance, and effectively lowers systemic blood pressure.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
46 mg/mL
(96.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- L-(-)-α-Methyldopa hydrate Solubility in DMSO
- L-(-)-α-Methyldopa hydrate Stock Solution
- L-(-)-α-Methyldopa hydrate Storage
- L-(-)-α-Methyldopa hydrate Stability
- L-(-)-α-Methyldopa hydrate Molecular Weight
- L-(-)-α-Methyldopa hydrate SMILES
- L-(-)-α-Methyldopa hydrate Chemical Structure (2D and 3D)
- L-(-)-α-Methyldopa hydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.