Clinical Trials

Numerous clinical trials, spanning Early Phase 1 through Phase 4, investigate kisspeptin-related signaling pathways and associated endocrine and metabolic interventions. These studies evaluate diverse conditions—including metabolic disease, reproductive phenomena, sterility, growth hormone disorders, and advanced solid tumors—and assess the impacts of kisspeptin-10 administration on reproductive axis responsiveness and glucose-stimulated insulin secretion. Conducted by academic institutions, medical centers, and pharmaceutical companies, these trials encompass recruitment statuses including completed, active, recruiting, terminated, and withdrawn.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07321028 ENROLLING_BY_INVITATION
Cellular Injury and Post-Cryogenic Recovery; Cryogenic Cellular Stress; Cold-Induced Cellular Injury; Thermal Injury Response; Post-Thaw Viability Impairment; Osmotic Stress Injury; Biomechanical Injury Modeling (In-Vitro); Blunt Force Injuries to the Extremities (Cellular Injury Model); Tissue Damage and Recovery Pathways; Hypothermic Tissue Stress; Cellular Regeneration and Repair
Truway Health, Inc.
 2025-12-10 EARLY_PHASE1
NCT00117936 NOT_YET_RECRUITING
Coronary Disease; Coronary Heart Disease; Myocardial Ischemia; Coronary Arteriosclerosis
Venturis Therapeutics, Inc.
 2027-09-01 PHASE2
NCT07593859 RECRUITING
Healthy Adult Participants
Northeastern University
 2026-02-01
NCT07659028 NOT_YET_RECRUITING
Prediabetes; Obesity & Overweight; Inflamation; Oxidative Stress
National and Kapodistrian University of Athens
 2026-07-01
NCT07658352 NOT_YET_RECRUITING
B-Cell Non-Hodgkin Lymphoma
Shanghai Helioson Pharmaceutical Co., Ltd.
 2026-06-26 PHASE1; PHASE2
NCT06914128 RECRUITING
MTAP-deleted Solid Tumors
Bayer
 2025-03-21 PHASE1; PHASE2
NCT07321106 RECRUITING
Colorectal Cancer; Colorectal Cancer (CRC); Colorectal (Colon or Rectal) Cancer; CRC; Metastatic Colon Cancer; Colon Cancer; Advanced Colorectal Cancer
Cartography Biosciences
 2026-01-15 PHASE1
NCT06841913 RECRUITING
Smoke Exposure; Influenza
University of North Carolina, Chapel Hill
 2025-09-26 PHASE4
NCT07775391 RECRUITING
Premature Ovarian Insufficiency
Shenzhen Wingor Biotechnology Co., Ltd.
 2026-08-03 PHASE1; PHASE2
NCT06956209 RECRUITING
Underactive Bladder
Iota Biosciences, Inc
 2025-09-24
NCT07418177 NOT_YET_RECRUITING
AMD - Age-Related Macular Degeneration
The First Affiliated Hospital with Nanjing Medical University
 2026-02-10 PHASE1; PHASE2
NCT05912621 RECRUITING
Obesity; Overweight and Obesity; Overweight
Stanford University
 2023-11-09 PHASE2
NCT07515066 NOT_YET_RECRUITING
Idiopathic Pulmonary Fibrosis (IPF)
Huan Ye
 2026-05-01 PHASE1
NCT07332455 RECRUITING
Neoplasms, Prostate
GlaxoSmithKline
 2026-02-10 PHASE1; PHASE2
NCT07180355 RECRUITING
Friedreich's Ataxia (FA)
Solid Biosciences Inc.
 2025-10-22 PHASE1
NCT07628127 RECRUITING
Obesity; Overweight
Verdiva Bio Dev Limited
 2026-07-06 PHASE1
NCT06053814 ACTIVE_NOT_RECRUITING
Duchenne Muscular Dystrophy
NS Pharma, Inc.
 2024-09-18 PHASE1; PHASE2
NCT07612891 RECRUITING
Breast Cancer (Locally Advanced or Metastatic); Advanced Solid Cancers; Metastatic (Stage IV) Breast Cancer; Ovarian Cancer; Endometrial Cancer
Shenzhen Ionova Life Sciences Co., Ltd.
 2025-07-04 PHASE1; PHASE2
NCT07222865 WITHDRAWN
Brain Imaging
Virginia Polytechnic Institute and State University
 2026-01
NCT05510830 NOT_YET_RECRUITING
Human Papilloma Virus Infection; Human Papilloma Virus Integration; Cervical Intraepithelial Neoplasia; Cervical Cancer; Cervical Conization
Tongji Hospital
 2022-10
NCT07454915 RECRUITING
Cervical Intraepithelial Neoplasia Grade 2/3; Human Papilloma Virus Infection Type 16
PapiVax Biotech, Inc.
 2026-04-01 PHASE2
NCT06872060 NOT_YET_RECRUITING
Kidney Diseases
Bispebjerg Hospital
 2026-06-01
NCT07649044 NOT_YET_RECRUITING
Smoking Cessation
The University of Hong Kong
 2026-06-27
NCT06544655 ACTIVE_NOT_RECRUITING
Advanced Solid Tumors
Bristol-Myers Squibb
 2024-10-10 PHASE1
NCT06148025 RECRUITING
Vaccine Response Impaired
South Australian Health and Medical Research Institute
 2023-11-23 PHASE4
NCT07555483 RECRUITING
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC
 2026-05-05 PHASE3
NCT05621668 ACTIVE_NOT_RECRUITING
Soft Tissue Sarcoma; Bone Sarcoma
M.D. Anderson Cancer Center
 2023-09-08 PHASE1
NCT07041801 RECRUITING
Systemic Lupus Erythematosus (SLE)
Shenzhen Beike Bio-Technology Co., Ltd.
 2025-06-28 PHASE1; PHASE2
NCT07164313 RECRUITING
Hepatocellular Carcinoma; Squamous Cell Non-Small Cell Lung Cancer; Germ Cell Tumor
Zymeworks BC Inc.
 2025-10-21 PHASE1
NCT05696561 RECRUITING
OAG - Open-Angle Glaucoma
New World Medical, Inc.
 2025-09-09
NCT05818683 RECRUITING
Metastatic Castration-resistant Prostate Neoplasms; Metastatic Hormone-sensitive Prostate Cancer
Janssen Research & Development, LLC
 2023-04-26 PHASE1
NCT05969041 RECRUITING
Epithelial Tumors, Malignant
Myeloid Therapeutics
 2023-08-02 PHASE1
NCT07060690 NOT_YET_RECRUITING
Depression Symptoms; Depression - Major Depressive Disorder; Depressive Disorder
Francesc Colom, PsyD, PhD
 2026-01
NCT07048405 RECRUITING
Brown Adipose Tissue; Cold Exposure; 18F-FDG PET/CT
University of Edinburgh
 2025-05-01
NCT03821935 ACTIVE_NOT_RECRUITING
Advanced Solid Tumors Cancer
AbbVie
 2019-02-21 PHASE1
NCT05332301 RECRUITING
Healthy Nutrition
Kirsten Bell
 2022-10-04
NCT05270213 RECRUITING
Advanced Cancer
Riboscience, LLC.
 2022-07-11 PHASE1
NCT06667687 ACTIVE_NOT_RECRUITING
Non-Hodgkin's Lymphoma
AbbVie
 2025-01-16 PHASE1
NCT06705322 NOT_YET_RECRUITING
Human Papillomavirus (HPV) Infection; Cervical Cancer
Fudan University
 2024-12-01 PHASE2
NCT05307939 RECRUITING
HPV; Oropharynx Cancer; HPV-Related Carcinoma; HPV-Related Malignancy; HPV Positive Oropharyngeal Squamous Cell Carcinoma
Memorial Sloan Kettering Cancer Center
 2022-03-24 PHASE2
NCT07150416 NOT_YET_RECRUITING
Multiple Pulmonary Ground-Glass Nodules; Lung Neoplasms; Precancerous Conditions
The First Affiliated Hospital of Guangzhou Medical University
 2025-10-01 PHASE2
NCT06667544 RECRUITING
KRAS G12D Mutation
Ranok Therapeutics (Hangzhou) Co., Ltd.
 2024-11-08 PHASE1; PHASE2
NCT06202261 RECRUITING
Metastatic Breast Cancer; Recurrent Breast Cancer; Advanced Malignancies
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
 2023-04-13 PHASE1; PHASE2
NCT04532489 RECRUITING
Radiotracer; Hypertension; Cholesterol
Benjamin Viglianti
 2021-01-18 EARLY_PHASE1
NCT06063850 RECRUITING
Mesial Temporal Lobe Epilepsy
UniQure Biopharma B.V.
 2024-06-12 PHASE1; PHASE2
NCT06635447 ACTIVE_NOT_RECRUITING
Breast Cancer
AstraZeneca
 2024-09-26 PHASE3
NCT07525089 ENROLLING_BY_INVITATION
VRE Colonization; CRE Colonization
BioMe Inc.
 2026-03-23
NCT07557979 NOT_YET_RECRUITING
Obesity (BMI>30)
Texas Tech University
 2026-05-15
NCT07149337 NOT_YET_RECRUITING
Aging; Kidney Disease; Mineral Metabolism
University of Zurich
 2025-09-30
NCT04101188 RECRUITING
Cardiovascular Risk Factor
University of Delaware
 2020-01-16
NCT06137157 COMPLETED
Netherton Syndrome
Azitra Inc.
 2024-06-16 PHASE1
NCT04711915 ACTIVE_NOT_RECRUITING
Major Depressive Disorder; Depression
Yale University
 2021-03-17 PHASE1
NCT06501196 RECRUITING
Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Preleukemia; Myelodysplastic Syndromes; Refractory Acute Myeloid Leukemia
BlossomHill Therapeutics
 2024-06-19 PHASE1
NCT06588257 COMPLETED
HPV
Fundación Huésped
 2024-10-09 PHASE4
NCT07118852 COMPLETED
Human Milk
University of Wisconsin, Madison
 2025-11-14
NCT06877208 ACTIVE_NOT_RECRUITING
Cerebral Glucose Metabolism
Nicolai Jacob Wewer Albrechtsen
 2025-03-18
NCT06939959 COMPLETED
Dry Eye; Insulin Sensitivity
Khyber Teaching Hospital
 2025-04-14 PHASE4
NCT07543627 ACTIVE_NOT_RECRUITING
Nurse Training; Geriatric; Communication Skills; EMPATHY İN NURSİNG
Gazi University
 2026-04-15
NCT05945628 ACTIVE_NOT_RECRUITING
Memory
University of Chicago
 2023-01-16
NCT07691177 COMPLETED
Type 2 Diabetes
Humanis Saglık Anonim Sirketi
 2026-02-06 PHASE1
NCT06799741 COMPLETED
DENV-3 Controlled Human Infection Model
AbViro LLC
 2025-01-07 PHASE2
NCT04803058 TERMINATED
Kidney Transplantation
ITB-Med LLC
 2022-12-14 PHASE2
NCT05698199 COMPLETED
Glioblastoma
Immunomic Therapeutics, Inc.
 2023-08-21 PHASE1
NCT06831929 RECRUITING
HPV Vaccine
University of California, Davis
 2025-02-28
NCT06011772 ACTIVE_NOT_RECRUITING
Colo-rectal Cancer
Roswell Park Cancer Institute
 2023-12-18 EARLY_PHASE1
NCT05600062 ACTIVE_NOT_RECRUITING
Acute Respiratory Distress Syndrome
Queen Mary University of London
 2023-03-21
NCT07784283 COMPLETED
Human Papillomavirus Vaccination; Cervical Cancer Prevention
Clinton Health Access Initiative Inc.
 2024-12-01
NCT06562361 UNKNOWN
MASH; PSC; Fibrostenotic Crohn's Disease; Healthy Volunteers
Antaros Medical
 2024-08 EARLY_PHASE1
NCT06731374 RECRUITING
Pneumococcal Disease; Pneumococcal Carriage
University of Oxford
 2025-02-24 PHASE4
NCT06126354 WITHDRAWN
Insulin Resistance; Prediabetic State; Non-Alcoholic Fatty Liver Disease; Overweight and Obesity
Columbia University
 2024-07-01 PHASE1
NCT07319221 COMPLETED
Detecting Number of Root Canal of Human Mandibular Second Molar
Future University in Egypt
 2024-11-29
NCT05424822 ACTIVE_NOT_RECRUITING
Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell
Janssen Research & Development, LLC
 2022-08-18 PHASE1
NCT06589128 RECRUITING
Digital Eye Strain (DES)
Universiti Sains Malaysia
 2024-10-01
NCT05203835 COMPLETED
Lymphedema of Upper Arm
Stanford University
 2022-07-27 PHASE2
NCT05634174 ACTIVE_NOT_RECRUITING
Obesity, Prediabetes
University of California, San Diego
 2023-08-01 PHASE1
NCT06156488 COMPLETED
Sinus Floor Augmentation
Universidad de Granada
 2023-09-04
NCT05997095 ACTIVE_NOT_RECRUITING
Skeletal Muscle Atrophy
University of Nottingham
 2023-05-22
NCT07344688 COMPLETED
Healhty
Universitas Padjadjaran
 2025-08-22
NCT06331559 TERMINATED
Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd.
 2024-03-19 PHASE1
NCT04710043 COMPLETED
Solid Tumor
BioNTech SE
 2021-06-08 PHASE1
NCT06866379 RECRUITING
Alcohol Use Disorder
Anders Fink-Jensen, MD, DMSci
 2025-05-07
NCT06082440 UNKNOWN
Osteoarthritis, Knee
First Affiliated Hospital of Wannan Medical College
 2023-11-22 EARLY_PHASE1
NCT06074705 TERMINATED
Advanced Solid Tumor
Daiichi Sankyo Co., Ltd.
 2023-08-04 PHASE1
NCT06650644 COMPLETED
Autism Spectrum Disorder
Miae Oh
 2024-10-10
NCT06525272 UNKNOWN
Pleurisy
Healthgen Biotechnology Corp.
 2024-07 PHASE1
NCT06724900 ACTIVE_NOT_RECRUITING
Wrinkles in Decolletage; Pigmentation; Décolleté Wrinkles
Krystal Biotech, Inc.
 2024-11-20 PHASE1; PHASE2
NCT05983627 NOT_YET_RECRUITING
Acute Respiratory Distress Syndrome
Asia Cell Therapeutics (Shanghai) Co., Ltd.
 2023-08-30 PHASE1
NCT07045636 COMPLETED
Microbial Colonization; Peri-Implantitis
Jamil awad shibli
 2025-05-11
NCT04193709 COMPLETED
Urinary Bladder, Neurogenic; Blood Pressure; Autonomic Dysreflexia; Bowel Incontinence
University of Louisville
 2021-01-04
NCT05232851 ACTIVE_NOT_RECRUITING
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Human Papillomavirus-Related Carcinoma; Locally Advanced Oropharyngeal Carcinoma; Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
Mayo Clinic
 2022-06-16 PHASE1; PHASE2
NCT06435936 ACTIVE_NOT_RECRUITING
PHA1A
SAb Biotherapeutics, Inc.
 2024-04-22 PHASE1
NCT06345755 COMPLETED
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Vertex Pharmaceuticals Incorporated
 2024-04-17 PHASE1
NCT04994912 COMPLETED
Healthy
Elixiron Immunotherapeutics (Hong Kong) Ltd.
 2021-10-01 PHASE1
NCT05555446 SUSPENDED
Celiac Disease; Gluten Sensitivity; Non-celiac Gluten Sensitivity
Milky Way Life Sciences LLC
 2022-09-22 EARLY_PHASE1
NCT06404905 RECRUITING
Advanced Solid Tumor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
 2024-01-24 PHASE1
NCT05275855 COMPLETED
Healthy Volunteers
Novartis Pharmaceuticals
 2022-04-29 PHASE1
NCT06467201 COMPLETED
Healthy Postmenopausal Women
Amneal Pharmaceuticals, LLC
 2024-06-03 PHASE1
NCT05511415 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2022-11-02
NCT03369223 COMPLETED
Advanced Cancer
Bristol-Myers Squibb
 2017-12-06 PHASE1; PHASE2
NCT06080048 COMPLETED
Ulcerative Colitis
Sorriso Pharmaceuticals, Inc.
 2023-10-24 PHASE1
NCT05291975 COMPLETED
Neuropathy, Diabetic; Neuropathy;Peripheral; Neuropathy, Painful
Erchonia Corporation
 2022-02-17
NCT05267899 UNKNOWN
Advanced Solid Tumors
Zhejiang Haichang Biotech Co., Ltd.
 2022-08-01 PHASE1
NCT04532801 WITHDRAWN
Insulin; Glucose; Healthy Volunteers; Women; Pregnancy
Stephanie B. Seminara, MD
 2019-09-01 PHASE1
NCT05436223 UNKNOWN
B-cell Non-Hodgkin's Lymphoma
Hrain Biotechnology Co., Ltd.
 2021-08-09 PHASE2
NCT05456854 WITHDRAWN
Metabolic Disease
Massachusetts General Hospital
 2022-06-03 PHASE1
NCT06212804 COMPLETED
Healthy Volunteers
Otsuka Pharmaceutical Development & Commercialization, Inc.
 2023-11-21 PHASE1
NCT05933525 COMPLETED
Diarrhea; Travelers Diarrhea; Infectious Diarrhea
Immuron Ltd.
 2023-05-29 PHASE2
NCT06090370 COMPLETED
Silicosis
Johns Hopkins University
 2024-01-24
NCT06909370 COMPLETED
Human Papilloma Virus (HPV)
Saglik Bilimleri Universitesi
 2024-05-01
NCT05613036 COMPLETED
Solid Tumors
Boehringer Ingelheim
 2023-01-03 PHASE1
NCT05907395 COMPLETED
Healthy Participants
Pfizer
 2023-08-09 PHASE1
NCT04763759 COMPLETED
Prosthetic Joint Infection
Trellis Bioscience LLC
 2021-02-08 PHASE1
NCT03950778 COMPLETED
Albumin Supplementation; Albumin Therapy; Sepsis
University of Pecs
 2023-03-04 EARLY_PHASE1
NCT05686733 COMPLETED
Aneurysms Saccular; Aneurysm, Ruptured; Aneurysm
Galaxy Therapeutics INC
 2022-01-26
NCT05901883 COMPLETED
Healthy
Celsius Therapeutics, Inc.
 2023-06-20 PHASE1
NCT05498597 UNKNOWN
Advanced Solid Tumor; Advanced Cancer; Advanced Carcinoma; Ovarian Cancer; Ovarian Carcinoma; Ovarian Epithelial Cancer; Ovarian Endometrioid Adenocarcinoma; Endometrial Cancer; Endometrial Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Endometrioid Adenocarcinoma; Endometrial Clear Cell Adenocarcinoma; Lung Adenocarcinoma; Triple Negative Breast Cancer; Pancreatic Ductal Adenocarcinoma; Malignant Pleural Mesothelioma; Ovarian Clear Cell Carcinoma; Ovarian Clear Cell Adenocarcinoma; Ovarian Mucinous Adenocarcinoma
Multitude Therapeutics Inc.
 2023-01-25 PHASE1
NCT05755685 UNKNOWN
Peritoneal Metastases; Colorectal Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2023-02-10 PHASE2
NCT04129710 UNKNOWN
Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL)
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2020-01-01 PHASE2
NCT04227496 UNKNOWN
Healthy; Pain
University College of Northern Denmark
 2020-01-13
NCT05954923 COMPLETED
Healthy
University Hospital, Gentofte, Copenhagen
 2023-09-05
NCT03493542 COMPLETED
Prevention of HPV Types 16- and 18-related Cervical Cancer, Cervical Intraepithelial Neoplasia (CIN) 1/2/3, and Cervical Adenocarcinoma in Situ
Merck Sharp & Dohme LLC
 2018-08-31 PHASE3
NCT05556967 COMPLETED
Adherence, Patient
University of Mississippi Medical Center
 2023-08-09 PHASE3
NCT03163511 COMPLETED
Type 1 Diabetes Mellitus With Hypoglycemia
ViaCyte
 2017-07-06 PHASE1; PHASE2
NCT03739645 TERMINATED
Fear Pain
Johns Hopkins University
 2020-08-01
NCT04963413 TERMINATED
Glioblastoma
University of Florida
 2022-01-13 PHASE1
NCT05883943 ACTIVE_NOT_RECRUITING
Venous Insufficiency of Leg
MED Institute Inc.
 2023-04-24
NCT05676801 UNKNOWN
Prosthesis and Implants; Surgical Site Infection; Prosthetic Joint Infection; Postoperative Wound Infection Deep Incisional Surgical Site
University of Zurich
 2023-02-04 EARLY_PHASE1
NCT05032599 TERMINATED
T-Cell Acute Lymphoblastic Leukemia
Beijing Boren Hospital
 2021-09-14 PHASE1
NCT04053283 COMPLETED
Metastatic Cancer; Epithelial Tumor
Akamis Bio
 2020-01-23 PHASE1
NCT04457778 COMPLETED
Metastatic Solid Tumors
EMD Serono Research & Development Institute, Inc.
 2020-07-10 PHASE1
NCT05090111 COMPLETED
NASH - Nonalcoholic Steatohepatitis
Aligos Therapeutics
 2021-12-01 PHASE1
NCT06281470 COMPLETED
Hyperkalemia
Waterstone Pharmaceutical (Wuhan) Co., LTD.
 2023-02-13 PHASE1
NCT05801653 COMPLETED
Healthy
Lund University
 2023-03-08
NCT05091684 TERMINATED
Hematological Patients; Bleeding; Platelet Refractoriness
Centre Hospitalier Universitaire de Saint Etienne
 2022-02-10 PHASE2
NCT05515614 COMPLETED
Premature Birth; Breastmilk Collection; Postnatal Growth Restriction
Loma Linda University
 2022-08-17
NCT04950101 COMPLETED
Human Papilloma Virus
Universitair Ziekenhuis Brussel
 2020-10-20
NCT04100200 ACTIVE_NOT_RECRUITING
Overweight or Obesity; Healthy
Clinical Nutrition Research Center, Illinois Institute of Technology
 2019-10-07
NCT04338659 COMPLETED
Advanced Malignant Tumors Lymphomas
Innovent Biologics (Suzhou) Co. Ltd.
 2021-01-14 PHASE1
NCT04014166 COMPLETED
Thrombocytopenia; Mesenchymal Stem Cells
Institute of Hematology & Blood Diseases Hospital, China
 2019-11-21
NCT04162639 WITHDRAWN
Burns
Virginia Commonwealth University
 2021-02 PHASE4
NCT04853017 COMPLETED
Minimal Residual Disease; KRAS G12D; KRAS G12R; NRAS G12D; NRAS G12R; Pancreatic Ductal Adenocarcinoma; Colorectal Cancer; Non-small Cell Lung Cancer; Ovarian Cancer; Cholangiocarcinoma; Bile Duct Cancer; Gallbladder Carcinoma
Elicio Therapeutics
 2021-10-04 PHASE1
NCT04880837 COMPLETED
Human Papillomavirus-Related Carcinoma
Ohio State University Comprehensive Cancer Center
 2022-04-27
NCT02703493 COMPLETED
Cancer of the Oropharynx
Northwell Health
 2010-03-01
NCT05448417 UNKNOWN
Non-invasive Ventilation; Healthy Subjects
Guangzhou Institute of Respiratory Disease
 2022-07-15
NCT04403763 TERMINATED
Presbyopia
AbbVie
 2020-07-27 PHASE1; PHASE2
NCT04561882 UNKNOWN
Atrial Septal Aneurysm
China National Center for Cardiovascular Diseases
 2020-09-04
NCT04920825 COMPLETED
Endocrine and Metabolic Secondary Hypertension
Universiti Sains Malaysia
 2021-05-01
NCT02341807 COMPLETED
Choroideremia; CHM (Choroideremia) Gene Mutations
Spark Therapeutics, Inc.
 2015-01-15 PHASE1; PHASE2
NCT05033444 COMPLETED
Traumatic Brain Injury (TBI)
Odyssey Group International, Inc.
 2022-02-09 PHASE1
NCT05252338 COMPLETED
Influenza
CureVac
 2022-02-07 PHASE1
NCT04753580 COMPLETED
Healthy Volunteers; Frail Volunteers
University Hospital, Clermont-Ferrand
 2021-10-04
NCT01659307 COMPLETED
Acute Lung Injury
Belfast Health and Social Care Trust
 2012-09 PHASE2
NCT03724747 COMPLETED
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Bayer
 2018-12-18 PHASE1
NCT06411743 COMPLETED
Hepatic Ascites
The First Hospital of Jilin University
 2021-09-07 PHASE2
NCT04696146 COMPLETED
End Stage Renal Disease; Chronic Kidney Diseases
Cedars-Sinai Medical Center
 2021-03-03 PHASE1; PHASE2
NCT03457701 COMPLETED
Anaemia
GlaxoSmithKline
 2019-07-30 PHASE2
NCT05372016 COMPLETED
HPV Infections; Cervical Cancer; Vulvar Cancer; Vaginal Cancer; CIN1; CIN2; CIN3; VaIN1; VaIN2; VaIN3; Genital Wart; VIN 1; VIN 2; VIN 3; AIS
Shanghai Bovax Biotechnology Co., Ltd.
 2020-09-19 PHASE3
NCT06517485 COMPLETED
Platinum Resistant Ovarian Cancer; Non-Small Cell Adenocarcinoma
Mersana Therapeutics
 2019-07-30 PHASE1
NCT04782895 COMPLETED
Cervical Cancer; Condylomata Acuminata
Xiamen University
 2021-03-14 PHASE3
NCT03788772 COMPLETED
Sepsis; Acute Circulatory Failure
Assistance Publique - Hôpitaux de Paris
 2019-07-15
NCT05506540 COMPLETED
Healthy
EnnovaBio
 2021-02-17 PHASE1
NCT05249374 COMPLETED
Hepatic Ascites
Beijing Protgen Biotechnology Development Co., Ltd.
 2021-10-14 PHASE1
NCT03972722 UNKNOWN
Cervical Cancer
Guangzhou Gloria Biosciences Co., Ltd.
 2019-05-15 PHASE2
NCT05490017 COMPLETED
Paroxysmal Nocturnal Hemoglobinuria
Kira Pharmacenticals (US), LLC.
 2020-12-30 PHASE1
NCT05308615 COMPLETED
COVID-19
Indonesia University
 2021-03-03
NCT04414592 UNKNOWN
Lumbar Disc Degeneration; Lumbar Disc Herniation
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
 2020-08
NCT04501744 COMPLETED
Malignant Ascites; Cancer
Wuhan YZY Biopharma Co., Ltd.
 2018-09-30 PHASE1
NCT06920589 COMPLETED
Human Papilloma Virus (HPV)
Hospital Univeristario Benemerita Universidad Autonoma de Puebla
 2021-12-01
NCT04644003 COMPLETED
Autism Spectrum Disorder
Stalicla SA
 2020-12-07 PHASE1
NCT04852029 TERMINATED
Infertility, Female
Reproductive Medicine Associates of New Jersey
 2021-08-16
NCT04670302 UNKNOWN
Supraspinatus Tear
Dr. Soetomo General Hospital
 2019-10-17
NCT04551443 UNKNOWN
Acute Myocardial Infarction
Navy General Hospital, Beijing
 2020-11-01 PHASE2
NCT04351672 COMPLETED
Overweight and Obesity
German Institute of Human Nutrition
 2020-06-23
NCT04690426 COMPLETED
Viral; Infection, Coxsackie(Virus)
Provention Bio, Inc.
 2020-12-14 PHASE1
NCT02947191 UNKNOWN
Chronic Nasal Septum Perforation
Chinese Academy of Sciences
 2016-11 PHASE1; PHASE2
NCT03477162 TERMINATED
Thoracic Neoplasm
Dartmouth-Hitchcock Medical Center
 2018-05-15 EARLY_PHASE1
NCT04557098 ACTIVE_NOT_RECRUITING
Hematological Malignancies
Janssen Research & Development, LLC
 2020-09-17 PHASE2
NCT05040113 COMPLETED
Healthy Adult Subjects
Connect Biopharm LLC
 2021-09-04 PHASE1
NCT03720457 UNKNOWN
CD19-positive; Diffuse Large B-cell Lymphoma; Follicular Lymphoma
Hrain Biotechnology Co., Ltd.
 2018-11-13 PHASE1
NCT04123886 COMPLETED
Malignant Pleural Effusion
Sichuan Clover Biopharmaceuticals, Inc.
 2020-01-08 PHASE1
NCT04414631 TERMINATED
Coronavirus Infections
University Hospital, Basel, Switzerland
 2020-08-06 PHASE2
NCT05536934 COMPLETED
Obese; Endothelial Function
Karolinska Institutet
 2016-12 EARLY_PHASE1
NCT03284723 TERMINATED
Breast Neoplasms
Pfizer
 2017-11-01 PHASE1
NCT04375046 UNKNOWN
COVID-19
Kafrelsheikh University
 2021-07 PHASE1
NCT04501796 TERMINATED
COVID-19
NeoImmuneTech
 2020-11-27 PHASE1
NCT05166941 COMPLETED
Psychiatric Nursing
Ankara Yildirim Beyazıt University
 2021-05-27
NCT06517433 COMPLETED
Platinum Resistant Ovarian Cancer; Non Small Cell Lung Cancer Metastatic
Mersana Therapeutics
 2017-12-12 PHASE1
NCT03422666 COMPLETED
Hyperlipidemias
University Health Network, Toronto
 2018-09-21 PHASE2; PHASE3
NCT02982772 COMPLETED
Smoking Cessation; HIV
dr. maria miguez
 2016-05
NCT04940910 UNKNOWN
Immunity
Chonbuk National University Hospital
 2021-02-22
NCT04898881 COMPLETED
Pain
Wayne State University
 2020-01-01 PHASE4
NCT06812351 COMPLETED
Randomized Clinical Trial
Ain Shams University
 2020-03-22 PHASE1
NCT04326868 COMPLETED
Helminths Infection; Drug Resistance
Centre de Recherche Médicale de Lambaréné
 2019-11-11 PHASE4
NCT02745808 UNKNOWN
Erectile Dysfunction; Type 1 Diabetes Mellitus; Type 2 Diabetes Mellitus
Chinese Academy of Sciences
 2015-09 PHASE1
NCT03313830 COMPLETED
Healthy
The University of Texas Medical Branch, Galveston
 2017-10-07
NCT04564144 UNKNOWN
Emesis
Mansoura University
 2020-06-01 PHASE1; PHASE2
NCT03607942 COMPLETED
Premature Infant
Société des Produits Nestlé (SPN)
 2018-08-06
NCT03746938 UNKNOWN
Heart Failure With Reduced Ejection Fraction
Viscofan
 2018-11-13 PHASE1
NCT03409107 COMPLETED
Anaemia
GlaxoSmithKline
 2018-03-05 PHASE3
NCT03947320 UNKNOWN
Hemophilia A
Sinocelltech Ltd.
 2019-12-20 PHASE3
NCT03829709 COMPLETED
HTLV-I Infections
Universidade Metodista de Piracicaba
 2019-01-30
NCT02824718 COMPLETED
Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment
Assistance Publique - Hôpitaux de Paris
 2017-06-06 PHASE2
NCT03970109 TERMINATED
Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2019-10-08 PHASE2
NCT04055246 COMPLETED
Prebiotics and Human Behavior and Cognition
Duke University
 2019-06-04
NCT04097938 COMPLETED
Healthy
Lakefront Biotherapeutics NV
 2019-09-18 PHASE1
NCT05246748 COMPLETED
Breastfeeding Education
Gamze Durmazoğlu
 2019-01-01
NCT04011319 UNKNOWN
Embryo Quality
Tang-Du Hospital
 2019-04-01
NCT03780582 UNKNOWN
Lung Cancer
Ensemble Group Holdings, LLC
 2018-12-14
NCT02385123 TERMINATED
Influenza; Influenza Immunisation
National Institute of Allergy and Infectious Diseases (NIAID)
 2015-04-01 PHASE4
NCT03291821 COMPLETED
Infertility, Female
IVI Madrid
 2017-12-01
NCT04007159 COMPLETED
Skin Care
GlaxoSmithKline
 2019-08-30
NCT03658655 COMPLETED
Type2 Diabetes
CAR-T (Shanghai) Biotechnology Co., Ltd.
 2018-06-01 EARLY_PHASE1
NCT03439488 COMPLETED
Chronic Hepatitis B
Alios Biopharma Inc.
 2018-03-26 PHASE1
NCT04075175 COMPLETED
Diphtheria
MassBiologics
 2019-04-23 PHASE1
NCT03796910 COMPLETED
Healthy Volunteers
Spero Therapeutics
 2018-12-18 PHASE1
NCT02232165 TERMINATED
Acute Spinal Cord Injury
University of Calgary
 2013-02
NCT03979690 COMPLETED
Colonic Polyp; Colon Adenoma; Colorectal Cancer
Bio-Medical Engineering (HK) Limited
 2019-06-12
NCT03794180 COMPLETED
Healthy Adult Subjects
I-Mab Biopharma US Limited
 2019-03-18 PHASE1
NCT04071574 COMPLETED
Female Infertility; Female Infertility Due to Ovulatory Disorder; Premature Ovarian Failure; Polycystic Ovary Syndrome; Female Infertility of Tubal Origin; Ectopic Pregnancy; Salpingitis; Female Infertility Due to Tubal Block; Female Infertility Due to Tubal Occlusion; Hydrosalpinx; Female Infertility - Cervical/Vaginal; Female Infertility Endocrine; Endometriosis; Fibroids; Congenital Uterine Anomaly; Infections Uterine; Female Infertility of Other Origin
Lebanese University
 2018-02-01 PHASE1; PHASE2
NCT03707990 COMPLETED
Obesity and Overweight
Novo Nordisk A/S
 2018-10-15 PHASE1
NCT03361605 COMPLETED
Healthy
University of Michigan
 2017-04-12 PHASE4
NCT02372175 COMPLETED
Dengue
U.S. Army Medical Research and Development Command
 2015-10 PHASE1
NCT02857283 COMPLETED
Environmental Exposure; Nasal Inflammation
University of North Carolina, Chapel Hill
 2017-04-22
NCT03801226 COMPLETED
Potential Applications for Heart Failure; Volume Overload
Yale University
 2018-12-01 EARLY_PHASE1
NCT02632266 COMPLETED
Complication of Prematurity
University of Kansas Medical Center
 2015-07 PHASE4
NCT02484092 COMPLETED
Hemophilia B
Pfizer
 2015-11-18 PHASE2
NCT03466073 COMPLETED
Community-acquired Pneumonia
BioAegis Therapeutics Inc.
 2018-08-28 PHASE1; PHASE2
NCT03231033 COMPLETED
Autoimmune Pulmonary Alveolar Proteinosis
Children's Hospital Medical Center, Cincinnati
 2017-08-17 PHASE1
NCT02251041 COMPLETED
Reperfusion Injury
Universitaire Ziekenhuizen KU Leuven
 2014-09 PHASE2
NCT03521258 UNKNOWN
Wounds; Trauma; Injury; Limb Salvage; Soft Tissue Injuries
Louisiana State University Health Sciences Center in New Orleans
 2016-02
NCT03063515 COMPLETED
Diabetes Mellitus
University of Miami
 2017-04-19 PHASE1
NCT02355925 COMPLETED
Infertility
Royan Institute
 2014-10 PHASE3
NCT03651024 UNKNOWN
Erectile Dysfunction (ED)
Sano V Pte Ltd
 2018-10
NCT02429037 UNKNOWN
Advanced Head and Neck Cancer
Shenzhen SiBiono GeneTech Co.,Ltd
 2015-05 PHASE2
NCT02561962 COMPLETED
Multiple Myeloma
Amgen
 2015-11-20 PHASE1
NCT03510091 COMPLETED
Human Papillomavirus Infection
Le Bonheur Children's Hospital
 2018-08-30
NCT03235349 COMPLETED
Hepatitis C Virus (HCV)
AbbVie
 2017-09-29 PHASE3
NCT02237846 WITHDRAWN
Osteoarthritis of the Knee
Translational Biosciences
 2014-09 PHASE1; PHASE2
NCT01578629 COMPLETED
Ischemic Stroke; Transient Ischemic Attack (TIA)
Andrew Slivka
 2012-03 PHASE1; PHASE2
NCT03369327 COMPLETED
Hepatitis C Virus Infection, Response to Therapy of; Human Immunodeficiency Virus
Tehran University of Medical Sciences
 2017-01-01 PHASE3
NCT03530436 COMPLETED
Safety After Oral Intake; Pharmacokinetics After Oral Intake
University of Hohenheim
 2018-06-07
NCT03392441 COMPLETED
Diabetes Mellitus, Type 1; Diabetes; Diabetes Complications
Mayo Clinic
 2017-11-30
NCT02267993 COMPLETED
Thrombocytopenia
Institute of Hematology & Blood Diseases Hospital, China
 2014-10 PHASE4
NCT03806829 COMPLETED
Endothelial Dysfunction
University of the Highlands and Islands
 2018-06-06
NCT02300909 COMPLETED
Scarring; Spinal Stenosis; Herniated Disc
MiMedx Group, Inc.
 2014-11
NCT03032588 COMPLETED
Healthy
Janssen Vaccines & Prevention B.V.
 2017-10-09 PHASE1
NCT02378779 TERMINATED
Premature Ejaculation
University Hospital, Brest
 2016-04-22
NCT03413267 COMPLETED
Food Structure Impact on Micronutrient Bioavailability
Françoise Nau
 2017-12-07
NCT03118349 TERMINATED
Pancreatic Carcinoma; Tumors That Express CA 19-9
BioNTech Research & Development, Inc.
 2017-06-01 PHASE1
NCT02057900 COMPLETED
Ischemic Heart Disease
Assistance Publique - Hôpitaux de Paris
 2013-05-27 PHASE1
NCT03328117 COMPLETED
Acute Lung Injury
Exvastat Ltd.
 2017-11-13 PHASE1
NCT02465359 COMPLETED
Chronic Inflammatory Demyelinating Polyneuropathy
University of South Florida
 2014-09
NCT03488992 COMPLETED
Metabolic Syndrome
USANA Health Sciences
 2017-01-10
NCT03428997 COMPLETED
Comedogenicity
Johnson & Johnson Consumer Inc. (J&JCI)
 2017-11-20
NCT02879877 COMPLETED
Healthy Volunteers
UCB Biopharma S.P.R.L.
 2016-07-11 PHASE1
NCT02877030 COMPLETED
HTLV-1
Pedreira, Érika, M.D.
 2017-04-02
NCT03394508 COMPLETED
Rhinitis; Asthma; Allergy
Karolinska Institutet
 2013-01 PHASE2; PHASE3
NCT03643380 COMPLETED
Overactive Bladder
Neuspera Medical, Inc.
 2017-08-17 PHASE1
NCT01941745 COMPLETED
Respiratory Distress Syndrome in Premature Infant; Bronchopulmonary Dysplasia
Tufts Medical Center
 2013-10 PHASE2
NCT01619020 COMPLETED
Healthy
Fred Hutchinson Cancer Center
 2012-10
NCT01814436 UNKNOWN
Dental Pulp Necrosis; Permanent Incisor Avulsed by Trauma
Air Force Military Medical University, China
 2013-02
NCT03198676 COMPLETED
Upper Respiratory Tract Infections
Prep Biopharm Limited
 2017-05-08 PHASE1
NCT03121339 COMPLETED
Seasonal Influenza Preventative Vaccine Pharmacodynamics
Vaxart
 2017-03-31 PHASE1
NCT02877667 COMPLETED
Tattoo
Soliton
 2016-07
NCT02789527 COMPLETED
Healthy
Estella S. Poloni
 2015-11
NCT02390466 UNKNOWN
HIV
InnaVirVax
 2015-04 PHASE1; PHASE2
NCT03294161 COMPLETED
Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis; American
Hospital Universitário Professor Edgard Santos
 2014-12 PHASE2
NCT02527096 COMPLETED
HIV-1 Infection
ANRS, Emerging Infectious Diseases
 2015-09-17 PHASE2
NCT02634528 COMPLETED
Diabetes Mellitus
Julphar Gulf Pharmaceutical Industries
 2016-11-16 PHASE1
NCT02244073 TERMINATED
Critical Illness
Hospices Civils de Lyon
 2015-05
NCT01754454 UNKNOWN
Acute GVH Disease
Affiliated Hospital to Academy of Military Medical Sciences
 2012-12 PHASE1; PHASE2
NCT02922673 COMPLETED
Endotoxemia
Radboud University Medical Center
 2016-09
NCT01751386 COMPLETED
Alcoholism; Alcohol Dependence; Alcohol Drinking Related Problems; Alcohol Drinking; Anxiety Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2012-12-03 PHASE2
NCT03558321 COMPLETED
Postmenopausal Bleeding
Cairo University
 2014-06
NCT02078193 COMPLETED
Kidney Transplantation
East Carolina University
 2013-11 PHASE4
NCT02312492 COMPLETED
Dyslipidemia
Tufts University
 2013-01
NCT02061722 COMPLETED
Huntington's Disease
CHDI Foundation, Inc.
 2013-01 EARLY_PHASE1
NCT02040558 TERMINATED
Advanced Solid Tumors
Mallinckrodt
 2013-07 PHASE1
NCT02321410 COMPLETED
Carotid Artery Disease; Plaque Neovascularization
Ospedale San Giovanni Bellinzona
 2014-02
NCT01783847 COMPLETED
Traumatic Optic Neuropathy
Tehran University of Medical Sciences
 2015-02 PHASE1; PHASE2
NCT02714166 COMPLETED
Sunscreening Agents
Bayer
 2016-02-26
NCT01375556 TERMINATED
Alcoholism; Genetics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
 2011-05-26 PHASE1
NCT02041975 COMPLETED
Obesity
University of Reading
 2013-10
NCT03330678 COMPLETED
Probiotics
Sanjay Gandhi Postgraduate Institute of Medical Sciences
 2013-12
NCT02439047 TERMINATED
Cancer
Centre Oscar Lambret
 2015-06
NCT01665573 COMPLETED
Fear Conditioning
Yale University
 2012-07-17 EARLY_PHASE1
NCT00957671 COMPLETED
Growth Hormone Deficiency; Traumatic Brain Injury
The University of Texas Medical Branch, Galveston
 2003-11 PHASE4
NCT02740790 COMPLETED
Human Papillomavirus
Shanghai Zerun Biotechnology Co.,Ltd
 2013-09 PHASE2
NCT01950325 COMPLETED
HIV-1 Infection; Neutralizing Antibody; Monoclonal Antibody; Viral Load; HIV Antibodies
National Institute of Allergy and Infectious Diseases (NIAID)
 2013-08-22 PHASE1
NCT03956433 COMPLETED
Metabolic Syndrome
University of Leeds
 2014-09-01
NCT02261168 COMPLETED
Diabetes Mellitus, Type 2; Insulin Resistance
Maastricht University Medical Center
 2014-11
NCT02059694 WITHDRAWN
Upper Eyelid Surgery
Duke University
NCT02080026 COMPLETED
Malaria
Radboud University Medical Center
 2014-06
NCT02338089 COMPLETED
Postpartum Hemorrhage
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
 2015-01
NCT01984801 COMPLETED
Acne Vulgaris
GlaxoSmithKline
 2013-10-14 PHASE1
NCT01988792 COMPLETED
Premature; Infant; Enteral Nutrition; Human Milk; Fortification
University of Tennessee
 2013-11
NCT02401113 COMPLETED
Sarcopenia
Pusan National University Hospital
 2014-11 PHASE2; PHASE3
NCT02549053 COMPLETED
Barrett Esophagus
University Hospital, Angers
 2012-02
NCT02320838 COMPLETED
Pain
University of Castilla-La Mancha
 2014-11
NCT01951508 COMPLETED
Healthy; Substance-related Disorder; Mood Disorder
University Hospital, Basel, Switzerland
 2013-10 EARLY_PHASE1
NCT01124981 COMPLETED
Fibrinogen Deficiency in Complex Cardiac Surgery
Isala
 2011-02 PHASE2; PHASE3
NCT02073656 COMPLETED
Hepatitis C Virus; HIV
Gilead Sciences
 2014-02 PHASE3
NCT02205554 COMPLETED
Pain
Syntrix Biosystems, Inc.
 2014-08 PHASE1
NCT01245322 COMPLETED
Bacterial Vaginosis
Skaraborg Hospital
 2007-01 PHASE4
NCT03315325 COMPLETED
Sterility, Reproductive
Quaid-e-Azam University
 2014-08-08 PHASE3
NCT03286517 COMPLETED
Reproductive Physiological Phenomena
Ghulam Nabi
 2014-06-26 PHASE3
NCT01386294 COMPLETED
HIV Prevention
CONRAD
 2011-10 PHASE3
NCT02018263 COMPLETED
Cocaine Dependence
Yale University
 2013-10 PHASE1
NCT01497197 TERMINATED
Infertility; Fertility; Follicle Stimulating Hormone Deficiency
Merck KGaA, Darmstadt, Germany
 2012-05 PHASE3
NCT01747980 COMPLETED
Gaucher Disease
Protalix
 2013-03 PHASE1
NCT01722526 COMPLETED
Human Acid Sphingomyelinase Deficiency
Genzyme, a Sanofi Company
 2013-03 PHASE1
NCT02017132 UNKNOWN
Obesity; Diabetes; Cardiovascular Disease
Queen Margaret University
 2013-04
NCT01218594 UNKNOWN
Non-small Cell Lung Cancer
Sun Yat-sen University
 2009-05 PHASE2
NCT03771326 COMPLETED
Kisspeptin Action on Insulin in Healthy Normal Men; Kisspeptin Action on Insulin in Obese Diabetic Men
Quaid-e-Azam University
 2013-10-29 PHASE3
NCT01685333 COMPLETED
Healthy
Azidus Brasil
 2013-02-28 PHASE1
NCT01483248 UNKNOWN
Liver Cirrhosis; Fibrosis; Liver Disease; Digestive System Disease
S-Evans Biosciences Co., Ltd.
 2010-10 PHASE1; PHASE2
NCT01437163 COMPLETED
Androgenetic Alopecia
Apira Science, Inc.
 2011-09
NCT01879813 COMPLETED
Cognitive Performance (Focus)
University of Leeds
 2012-10
NCT01734057 WITHDRAWN
Purpura; Idiopathic Thrombocytopenic Purpura
Shandong University
 2012-07 PHASE3
NCT01009567 COMPLETED
Ovarian Hyperstimulation Syndrome
Royan Institute
 2009-06 PHASE1; PHASE2
NCT00719212 COMPLETED
Ovarian Neoplasms
Translational Research in Oncology
 2009-01 PHASE2
NCT01305356 COMPLETED
Degenerative Joint Disease; Congenital Deformity; Arthritis; Osteoarthritis; Rheumatoid Arthritis
BioMimetic Therapeutics
 2011-03
NCT02974894 COMPLETED
Stress Reaction
Lund University
 2013-02
NCT00313716 COMPLETED
Anemia; Traumatic Brain Injury
Claudia Sue Robertson
 2006-04 PHASE2; PHASE3
NCT02133495 COMPLETED
Lower Eyelid Retraction
SGM Physician Research Consortium
 2011-01
NCT01007071 COMPLETED
Hypopituitarism
Stanford University
 2009-11-01 PHASE3
NCT01624038 UNKNOWN
Thalassemia Intermedia
Ain Shams University
 2012-06 PHASE2; PHASE3
NCT01312246 WITHDRAWN
Colon and Rectal Diseases
University of Illinois at Chicago
 2011-04
NCT01271829 COMPLETED
Satiety; Glycemic Index; Insulin; Gastrointestinal Peptides and Hormones
Loma Linda University
 2011-01
NCT01341912 COMPLETED
Severe Hemophilia A
Octapharma
 2011-06 PHASE3
NCT02025686 COMPLETED
Pain; Inflammation; Hyperalgesia
Per Rotbøll Nielsen
 2012-03
NCT01735370 COMPLETED
Fasting
IPCA Laboratories Ltd.
 2012-05 PHASE1
NCT01649024 UNKNOWN
Malignant Mesothelioma
Azienda Ospedaliera Universitaria Senese
 2009-05 PHASE2
NCT01490762 COMPLETED
Healthy
Mannkind Corporation
 2011-12 PHASE1
NCT01503216 COMPLETED
Vitamin D Deficiency
Ulrike Lehmann
 2012-01
NCT01438749 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
 2011-10 PHASE1
NCT00722839 COMPLETED
Nonneoplastic Condition
City of Hope Medical Center
 2006-12 PHASE1
NCT01268150 COMPLETED
Locally Recurrent; Metastatic Breast Cancer ( HER2 Negative)
Eisai Inc.
 2011-02 PHASE2
NCT00604175 COMPLETED
HIV Infections; Sexually Transmitted Diseases
National Institute of Allergy and Infectious Diseases (NIAID)
 2008-02 PHASE2
NCT01356823 COMPLETED
Cervical Intraepithelial Neoplasia; Cervical Cancer
Xiamen University
 2011-03 PHASE2
NCT01265875 COMPLETED
Chronic Pancreatitis
ChiRhoClin, Inc.
 2010-12 PHASE1; PHASE2
NCT00989196 COMPLETED
Hemophilia A
Octapharma
 2010-05 PHASE2
NCT01416324 COMPLETED
Diabetes Mellitus, Type 2
GlaxoSmithKline
 2011-06-15 PHASE1
NCT01106729 COMPLETED
Metabolism and Clearance of Cyanidin 3 Glucoside
University of East Anglia
 2011-07
NCT01367886 COMPLETED
Overactive Bladder
Washington University School of Medicine
 2010-08
NCT01056549 COMPLETED
Hyperlipidemia
University Health Network, Toronto
 2010-01
NCT01334151 COMPLETED
Diabetes Mellitus Type 1
Biodel
 2011-03 PHASE1
NCT01342250 COMPLETED
Liver Cirrhosis
Shenzhen Beike Bio-Technology Co., Ltd.
 2010-10 PHASE1; PHASE2
NCT03209895 COMPLETED
Joint Pain
U.S. Nutraceuticals, LLC
 2010-10-08
NCT04874324 COMPLETED
Pharmacokinetics
Wockhardt
 2011-03-17 PHASE1
NCT01310478 UNKNOWN
Colorectal Neoplasm
Fudan University
 2010-08 PHASE1
NCT00953472 TERMINATED
Hypertension Stage 1
Mayo Clinic
 2009-02 PHASE1
NCT00250211 COMPLETED
Glioblastoma; Glioma
AHS Cancer Control Alberta
 2005-03 PHASE1; PHASE2
NCT01380366 COMPLETED
Short Bowel Syndrome
Northwestern University
 2006-10 PHASE4
NCT03409510 COMPLETED
Healthy Volunteers
Bispebjerg Hospital
 2010-11-01
NCT01691469 COMPLETED
Healthy
Dr. Reddy's Laboratories Limited
 2011-01 PHASE1
NCT00283400 TERMINATED
Subarachnoid Hemorrhage
Baylor College of Medicine
 2006-01
NCT00181610 COMPLETED
Lactation
Massachusetts General Hospital
 2004-09 PHASE2
NCT01011296 COMPLETED
Healthy Volunteers
Pfizer
 2009-12 PHASE1
NCT00513526 COMPLETED
Infection; Precancerous Condition
AIDS Malignancy Consortium
 2007-11 PHASE2
NCT00570960 TERMINATED
Spontaneous Bacterial Peritonitis
University of Virginia
 2007-06 PHASE4
NCT00916448 COMPLETED
Endotoxemia; Inflammation; Multi Organ Dysfunction Syndrome; Sepsis
Radboud University Medical Center
 2009-05
NCT00600054 COMPLETED
Recurrent Diffuse Pontine Gliomas
YM BioSciences
 2007-10 PHASE2
NCT00292981 COMPLETED
Hereditary Angioedema
CSL Behring
 2005-08 PHASE3
NCT00972582 COMPLETED
Healthy
The Hospital for Sick Children
 2009-05 PHASE1
NCT00548444 COMPLETED
Tuberculosis
University of Oxford
 2007-10 PHASE1
NCT01060722 COMPLETED
Healthy
OPKO Health, Inc.
 2009-10 PHASE1
NCT00646568 COMPLETED
Infertility
Hadassah Medical Organization
 2008-06
NCT00832663 COMPLETED
Muscle Damage
Bispebjerg Hospital
 2009-04
NCT00773175 COMPLETED
Dehydration
Halozyme Therapeutics
 2008-10 PHASE4
NCT00910390 COMPLETED
Human Embryo Cryopreservation
Erasme University Hospital
 2009-04
NCT00858923 UNKNOWN
HIV; HIV Infections
Energex Systems, Inc.
 2008-07 PHASE1
NCT00776165 COMPLETED
Chemotherapy-Induced Neutropenia
Shantha Biotechnics Limited
 2007-10 PHASE3
NCT00356486 COMPLETED
HIV Infections
Germans Trias i Pujol Hospital
 2005-10 PHASE4
NCT00774800 COMPLETED
Type 1 Diabetes Mellitus
Halozyme Therapeutics
 2008-10 PHASE2
NCT00582010 COMPLETED
Reperfusion Injury; Liver Injury
University of Alabama at Birmingham
 2008-04 PHASE2; PHASE3
NCT01513057 COMPLETED
Healthy
Dr. Reddy's Laboratories Limited
 2009-01 PHASE1
NCT00348387 COMPLETED
Poliomyelitis; Polio
Sanofi Pasteur, a Sanofi Company
 2006-06 PHASE3
NCT00613379 COMPLETED
HIV Infections
CytoDyn, Inc.
 2007-12 PHASE2
NCT00668538 COMPLETED
Healthy
University of Southern Denmark
 2008-04
NCT00808704 COMPLETED
Hypoxic-Ischemic Encephalopathy
Zhengzhou University
 2003-08 PHASE1; PHASE2
NCT00003993 COMPLETED
Lymphoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
National Institute on Aging (NIA)
 1999-09 PHASE1
NCT00246012 COMPLETED
Melanoma
Centocor, Inc.
 2005-05 PHASE1; PHASE2
NCT00437112 COMPLETED
Diabetes Mellitus, Type 2
Eli Lilly and Company
 2007-02 PHASE3
NCT00585650 COMPLETED
Psoriasis
University of California, Irvine
 2007-05 PHASE1; PHASE2
NCT01996475 COMPLETED
Healthy
Torrent Pharmaceuticals Limited
 PHASE1
NCT00618839 COMPLETED
Third Degree Burn; Burns; Wound Infection; Degloving Injury
Stratatech, a Mallinckrodt Company
 2006-07 PHASE1; PHASE2
NCT00636038 COMPLETED
Vitamin A Status
Tufts University
 2008-01 PHASE1
NCT00718653 COMPLETED
Eye Health
National Eye Institute (NEI)
 2004-09
NCT00260234 TERMINATED
Diabetes Mellitus, Type 1
Novocell
 2005-11 PHASE1; PHASE2
NCT00954824 COMPLETED
Metabolic Syndrome X
University of Pennsylvania
 2003-08
NCT00479258 TERMINATED
Diabetes Mellitus, Type 1
Pfizer
 2007-10 PHASE3
NCT00071240 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
 2002-10 PHASE2
NCT00846950 COMPLETED
Cognition
Maastricht University Medical Center
 2006-12
NCT00325130 COMPLETED
Neoplasms, Glandular and Epithelial; Diphtheria; Tetanus; Whooping Cough; Meningitis
Merck Sharp & Dohme LLC
 2006-04 PHASE3
NCT00274703 COMPLETED
Oesophagitis, Eosinophilic
GlaxoSmithKline
 2005-12 PHASE2
NCT00392457 COMPLETED
Kallmann Syndrome; Hypogonadism; Gonadal Disorder
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
 1995-07
NCT01267396 COMPLETED
Healthy
Dr. Reddy's Laboratories Limited
 2006-09 PHASE1
NCT01687556 COMPLETED
Acne Vulgaris
Seoul National University Hospital
 2005-07
NCT00206934 COMPLETED
Healthy Volunteers
University of Copenhagen
 2005-03
NCT00079898 COMPLETED
Healthy
National Center for Complementary and Integrative Health (NCCIH)
 2002-07
NCT02090933 COMPLETED
No Evidence of Disease
National Cancer Institute (NCI)
 2004-03 PHASE2
NCT01494493 TERMINATED
Degenerative Disc Disease
Medtronic Spinal and Biologics
 2000-09
NCT00853190 COMPLETED
Healthy
Mallinckrodt
 2003-09 PHASE1
NCT00778583 COMPLETED
Healthy
Ranbaxy Laboratories Limited
 2003-09
NCT01448070 COMPLETED
Diabetes; Healthy
Novo Nordisk A/S
 2002-10-15 PHASE1
NCT00775827 COMPLETED
Healthy
Ranbaxy Laboratories Limited
 2002-11
NCT00001309 COMPLETED
Healthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 1997-01-23 PHASE1
NCT00137891 COMPLETED
Healthy
Genzyme, a Sanofi Company
 2005-06 PHASE1
NCT00297960 COMPLETED
Healthy Male Volunteers
Medical University of Vienna
 2005-04 PHASE4
NCT00021580 UNKNOWN
Diabetes Mellitus
National Center for Research Resources (NCRR)
 PHASE1
NCT00000683 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
 PHASE1
NCT00000845 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
 PHASE1
NCT01418586 COMPLETED
Healthy
Torrent Pharmaceuticals Limited
 PHASE1
NCT00004401 COMPLETED
Infant Botulism; Botulism
California Department of Health Services
 1998-01
NCT00140374 COMPLETED
Prostate Cancer
Cell Genesys
 1998-12 PHASE1; PHASE2
NCT00155935 UNKNOWN
Ovarian Cancer
National Taiwan University Hospital
 2004-01
NCT00507364 UNKNOWN
Biological Therapy for Chronic Anal Fissure; Treatment by Biological Factors - Activated Macrophages; Interventional Study
Hadassah Medical Organization
 PHASE3
NCT00000684 COMPLETED
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)
NCT01218711 COMPLETED
Healthy
Torrent Pharmaceuticals Limited
 PHASE1

(data from https://clinicaltrials.gov, updated on 2026-01-06)

Check the Kisspeptin-10 (human) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Kisspeptin-10 binds to the G-protein coupled receptor GPR54, triggering downstream NFATc4-mediated BMP2 signaling while inhibiting pro-angiogenic cascades to induce osteoblast differentiation and suppress endothelial capillary formation. This attenuation of cellular motility and vascularization halts invasive cell phenotypes, mediating tumor metastasis suppression in advanced solid tumors and regulating hormonal axis responsiveness in reproductive and metabolic disorders.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Jump to

Note: Technical data last updated: Sep 1, 2026.