CAS No. 1125-21-9

Batch: Purity:99.93
Ketoisophorone Chemical Structure
Chemical Structure
Check the Ketoisophorone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1125-21-9
Molecular Formula

C9H12O2

Molecular Weight (MW) 152.19
SMILES CC1=CC(=O)CC(C1=O)(C)C

Ordering Information

Biological Activity

Ketoisophorone (4-Oxoisophorone) is a naturally occurring monoterpene ketone and a primary volatile constituent of saffron (*Crocus sativus*). It serves as a key bioactive flavor compound and an enzymatic substrate in microbial biotransformation pathways, particularly mediated by enoate reductases and Old Yellow Enzymes. Downstream, ketoisophorone conversion modulates oxidative stress responses and contributes to the overall antioxidant profile of saffron-derived constituents.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 30 mg/mL (197.12 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.