CAS No. 2769053-56-5

Batch: Purity:99.01
KDS-12025 Chemical Structure
Chemical Structure
Check the KDS-12025 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 2769053-56-5
Molecular Formula

C16H20N2O

Molecular Weight (MW) 256.34

Ordering Information

Biological Activity

KDS-12025 is a blood-brain barrier-permeable small molecule that acts as a potent enhancer of hemoglobin pseudoperoxidase activity. By stimulating the intrinsic pseudoperoxidase catalytic reaction of hemoglobin, this compound promotes efficient hydrogen peroxide decomposition even under conditions of low hemoglobin availability. Consequently, enhancing hemoglobin pseudoperoxidase activity helps attenuate reactive oxygen species accumulation and cellular oxidative stress within brain tissue microenvironments.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 51 mg/mL (198.95 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.