CAS No. 6730-83-2
Batch:
Purity:99.78
Chemical Structure
Check the
Kaurenoic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 6730-83-2 | |
|---|---|---|
| Molecular Formula |
C20H30O2 |
|
| Molecular Weight (MW) | 302.45 | |
| SMILES | CC12CCCC(C1CCC34C2CCC(C3)C(=C)C4)(C)C(=O)O |
Kaurenoic acid is a natural diterpenoid that acts as an anti-inflammatory agent by suppressing the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Downstream, attenuation of these enzymes suppresses the production of pro-inflammatory mediators, including nitric oxide and prostaglandin E2, through inhibition of NF-kB pathway signaling. Consequently, kaurenoic acid attenuates cellular inflammatory responses in macrophage models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
60 mg/mL
(198.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| DMSO |
60 mg/mL
(198.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 40 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.