CAS No. 200132-83-8
Batch:
Purity:99.80
Chemical Structure
Check the
Kasugamycin hydrochloride hydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 200132-83-8 | |
|---|---|---|
| Molecular Formula |
C14H28ClN3O10 |
|
| Molecular Weight (MW) | 433.84 | |
| SMILES | O.Cl.CC1OC(OC2C(O)C(O)C(O)C(O)C2O)C(N)CC1NC(=N)C(O)=O |
Kasugamycin hydrochloride hydrate is an aminoglycoside antibiotic that functions as a translation inhibitor. It specifically binds to the 30S and 70S ribosomal subunits, disrupting the mRNA-tRNA codon-anticodon interaction at the peptidyl (P) site. This action selectively inhibits translation initiation of canonical messenger RNAs while sparing leaderless mRNAs, leading to downstream inhibition of bacterial protein synthesis and bacterial growth suppression. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 87 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Kasugamycin hydrochloride hydrate Solubility in DMSO
- Kasugamycin hydrochloride hydrate Stock Solution
- Kasugamycin hydrochloride hydrate Storage
- Kasugamycin hydrochloride hydrate Stability
- Kasugamycin hydrochloride hydrate Molecular Weight
- Kasugamycin hydrochloride hydrate SMILES
- Kasugamycin hydrochloride hydrate Chemical Structure (2D and 3D)
- Kasugamycin hydrochloride hydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.