CAS No. 521-88-0
Batch:
Purity:99.11
Chemical Structure
Check the
Karanjin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 521-88-0 | |
|---|---|---|
| Molecular Formula | ||
| Molecular Weight (MW) | 292.29 |
Biological Activity
Karanjin is an orally active furanoflavonoid isolated from Leguminosae species that functions as a natural bioactive agent with anti-inflammatory, antioxidant, and anti-cancer activities. It modulates key signaling pathways, including NF-kB and Nrf2, leading to the downregulation of pro-inflammatory cytokines and attenuation of oxidative stress. Downstream, Karanjin demonstrates protective cellular and systemic phenotypes across gastrointestinal, metabolic, and neurodegenerative disease models, as well as insecticidal and acaricidal properties.
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
10 mg/mL
(34.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Jump to
Note: Technical data last updated: Sep 1, 2026.