CAS No. 40437-72-7

Batch: Purity:99.69
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Kaempferol-3-O-glucorhamnoside Chemical Structure
Chemical Structure
Check the Kaempferol-3-O-glucorhamnoside product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 40437-72-7
Molecular Formula

C27H30O15
Molecular Weight (MW) 594.52
SMILES CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=C(OC4=CC(=CC(=C4C3=O)O)O)C5=CC=C(C=C5)O)CO)O)O)O)O)O

Ordering Information

Biological Activity

Kaempferol-3-O-glucorhamnoside is a natural flavonoid glycoside that displays insulin-like glucose-lowering activity. The compound stimulates cellular glucose uptake and accelerates glycogen synthesis through the activation of the PI3K/AKT and MAPK/ERK signaling pathways. By promoting GLUT4 translocation and enhancing intracellular glucose metabolism in peripheral tissues, Kaempferol-3-O-glucorhamnoside effectively lowers blood glucose levels and exhibits prominent anti-hyperglycemic properties. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO 2 mg/mL (3.36 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol 1 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.