CAS No. 491-54-3

Batch: Purity:99.93
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Kaempferide Chemical Structure
Chemical Structure
Check the Kaempferide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 491-54-3
Molecular Formula

C16H12O6
Molecular Weight (MW) 300.26
SMILES COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O

Ordering Information

Biological Activity

Kaempferide is a natural O-methylated flavonoid compound derived from Kaempferia galanga with anti-inflammatory, antioxidant, and anti-carcinogenic properties. It targets key cellular cascades by inhibiting the MAPK and NF-kB signaling pathways, resulting in reduced reactive oxygen species production and downregulation of downstream pro-inflammatory mediators. Through these signaling modulations, kaempferide suppresses cell proliferation and promotes cell cycle arrest and apoptosis in cancer cell lines. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 60 mg/mL (199.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.