CAS No. 756875-51-1
Batch:
Purity:99.50
Chemical Structure
Check the
K6PC-5
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N-(1,3-dihydroxypropan-2-yl)-2-hexyl-3-oxodecanamide | |
|---|---|---|
| CAS Number | 756875-51-1 | |
| Molecular Formula |
C19H37NO4 |
|
| Molecular Weight (MW) | 343.50 | |
| InChIKey | CGYVFCHCRBGGJG-UHFFFAOYSA-N |
Biological Activity
K6PC-5 is a ceramide derivative that functions as an activator of sphingosine kinase 1 (SPHK1). Activation of SPHK1 increases intracellular sphingosine-1-phosphate (S1P) production and induces transient intracellular calcium mobilization, downstream signaling pathways that promote keratinocyte and epidermal differentiation. Elevated intracellular S1P generation mediated by K6PC-5 also attenuates viral entry and viral protein production in cellular models of infection. [1][2]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
69 mg/mL
(200.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 69 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.