SMILES:
OC1=CC=C(F)C=C1C(N2CC3=C(C=C(C=C3)C4=CC=C(C=C4)N5CCNCC5)C2=O)C(=O)NC6=NC=CS6
Chemical Structure
Check the
(Rac)-JBJ-04-125-02
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-(5-fluoro-2-hydroxyphenyl)-2-[3-oxo-5-(4-piperazin-1-ylphenyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)acetamide | |
|---|---|---|
| CAS Number | 2140807-05-0 | |
| Molecular Formula |
C29H26FN5O3S |
|
| Molecular Weight (MW) | 543.61 | |
| SMILES | OC1=CC=C(F)C=C1C(N2CC3=C(C=C(C=C3)C4=CC=C(C=C4)N5CCNCC5)C2=O)C(=O)NC6=NC=CS6 | |
| InChIKey | VHQVOTINPRYDAO-UHFFFAOYSA-N |
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(183.95 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.