CAS No. 32434-44-9

Batch: Purity:
Isofebrifugin Chemical Structure
Chemical Structure
Check the Isofebrifugin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 32434-44-9
Molecular Formula

C16H19N3O3

Molecular Weight (MW) 301.34

Ordering Information

Biological Activity

Isofebrifugine is a natural quinazolinone alkaloid that functions as a potent antimalarial agent against Plasmodium parasites. It displays high stereospecific antiplasmodial activity in vitro against Plasmodium falciparum. Furthermore, treatment involving isofebrifugine in alkaloid mixtures effectively suppresses blood-stage parasitemia and enhances clearance in chloroquine-resistant Plasmodium berghei infection models, highlighting its potential utility in overcoming drug-resistant malaria.[1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.