CAS No. 2450-53-5

Batch: Purity:99.57
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Isochlorogenic acid A Chemical Structure
Chemical Structure
Check the Isochlorogenic acid A product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 2450-53-5
Molecular Formula

C25H24O12
Molecular Weight (MW) 516.45
SMILES C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)OC(=O)C=CC3=CC(=C(C=C3)O)O

Ordering Information

Biological Activity

Isochlorogenic acid A is a natural polyphenolic compound that functions as a potent hepatoprotective and antiviral agent. It significantly upregulates heme oxygenase-1 (HO-1) expression, suppressing hepatitis B virus DNA replication and viral antigen secretion. Downstream upregulation of HO-1 and attenuation of inflammatory signaling reduce oxidative stress, thereby preserving cellular viability and protecting against hepatic injury. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (193.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.