CAS No. 20784-50-3
Batch:
Purity:99.04
Chemical Structure
Check the
Isobavachalcone
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 20784-50-3 | |
|---|---|---|
| Molecular Formula |
C20H20O4 |
|
| Molecular Weight (MW) | 324.37 | |
| SMILES | CC(=CCC1=C(C=CC(=C1O)C(=O)C=CC2=CC=C(C=C2)O)O)C |
Isobavachalcone is a naturally occurring chalcone derived from Psoralea corylifolia that acts as an inhibitor of the AKT signaling pathway. It suppresses AKT phosphorylation and downregulates downstream signaling within the AKT/mTOR pathway. This inhibition impairs cell proliferation, suppresses migration, and induces apoptotic cell death in various cancer cell lines. Additionally, Isobavachalcone demonstrates antibacterial and anti-inflammatory activities. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
64 mg/mL
(197.3 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 64 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.