CAS No. 67814-76-0

Batch: Purity:97
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Isepamicin Sulphate Chemical Structure
Chemical Structure
Check the Isepamicin Sulphate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 67814-76-0
Molecular Formula

C22H45N5O16S
Molecular Weight (MW) 667.68
SMILES CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(C(C(C(O3)CN)O)O)O)N)NC(=O)C(CN)O)O.OS(=O)(=O)O

Biological Activity

Isepamicin Sulphate is an aminoglycoside antibiotic that targets the bacterial 30S ribosomal subunit to inhibit bacterial protein synthesis. By binding to the 30S ribosomal subunit, it disrupts normal translational fidelity and mRNA decoding, leading to aberrant protein expression and impaired cell wall integrity. Consequently, this compound exhibits broad-spectrum antibacterial activity against various Gram-negative bacterial pathogens by effectively suppressing bacterial growth and proliferation.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.