CAS No. 305-33-9
Batch:
Purity:99.98
Chemical Structure
Check the
Iproniazid phosphate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | phosphoric acid;N'-propan-2-ylpyridine-4-carbohydrazide | |
|---|---|---|
| CAS Number | 305-33-9 | |
| Molecular Formula |
C9H16N3O5P |
|
| Molecular Weight (MW) | 277.21 | |
| SMILES | CC(C)NNC(=O)C1=CC=NC=C1.O[P](O)(O)=O | |
| InChIKey | YPDVTKJXVHYWFY-UHFFFAOYSA-N |
Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor. By covalently binding to monoamine oxidase enzymes, it prevents the oxidative deamination and degradation of monoamine neurotransmitters, including serotonin, dopamine, and norepinephrine. This inhibition elevates synaptic monoamine concentrations, enhancing central neurotransmission and downstream signaling pathways involved in mood regulation, thereby producing antidepressant effects in biological models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
55 mg/mL
(198.4 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 55 mg/mL |
| Ethanol | 5 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.