CAS No. 951382-34-6

Batch: Purity:99.37
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Ipragliflozin L-Proline Chemical Structure
Chemical Structure
Check the Ipragliflozin L-Proline product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol;(2S)-pyrrolidine-2-carboxylic acid
CAS Number 951382-34-6
Molecular Formula

C26H30FNO7S
Molecular Weight (MW) 519.58
SMILES C1CC(NC1)C(=O)O.C1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)F
InChIKey TUVGWWULBZIUBS-FVYIYGEMSA-N

Ordering Information

Biological Activity

Ipragliflozin L-Proline is an orally active and selective inhibitor of human SGLT2 (IC50 7.38 nM), rat SGLT2 (IC50 6.73 nM), and mouse SGLT2 (IC50 5.64 nM). By selectively targeting SGLT2 transporters in renal proximal tubules, it suppresses renal glucose reabsorption, thereby enhancing urinary glucose excretion and effectively reducing blood glucose levels in animal models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 35 mg/mL (67.36 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 6 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.